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Syracuse vs Clemson Odds

Syracuse
19.0 Pts
Clemson
36.5 Pts
Saturday September 20, 2025 at 12:00 PM ET
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Moneyline
DraftKings DraftKings
-800
PROBABILITY with vig removed
Syr Orange Win (+550)
14.8%
Clem Tigers Win (-800)
85.2%
LINE MOVEMENT
Spread
DraftKings DraftKings
-17.5
PROBABILITY with vig removed
Syr Win or Lose By < 18 Pts(-112)
50.4%
Clem Win By 18+ Pts(-108)
49.6%
LINE MOVEMENT
Over Under
DraftKings DraftKings
55.5
Points
PROBABILITY with vig removed
Over 56 Total Points(-108)
49.6%
Under 56 Total Points(-112)
50.4%
LINE MOVEMENT
Syr
Orange Injury Report
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Clem
Tigers Injury Report
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Syr
Orange News
#1 TE
Dan Villari: Slows down in Week 3
Sep 15th
Villari gathered in all four targets for 40 yards during Friday's 66-24 victory versus Colgate.
#1 QB
Steve Angeli: Six TDs in win
Sep 15th
Angeli completed 23 of 31 passes for 382 yards and five touchdowns during Friday's 66-24 victory over Colgate. He also had six rushes for 21 yards with one touchdown.
#2 QB
Rickie Collins: Sees blowout run
Sep 15th
Collins completed 3 of 5 passes for 30 yards, one touchdown and one interception during Friday's 66-24 victory versus Colgate.
#2 RB
Will Nixon: Shows well in lead role
Sep 15th
Nixon tallied 12 carries for 66 yards and one touchdown during Friday's 66-24 win over Colgate.
#3 WR
Justus Ross-Simmons: Quiet in blowout
Sep 15th
Ross-Simmons caught their only target for 26 yards and one touchdown during Friday's 66-24 win versus Colgate.
#2 WR
Darrell Gill: Monster game in Week 3
Sep 15th
Gill accrued six receptions (on nine targets) for 152 yards and two touchdowns during Friday's 66-24 win over Colgate.
#10 WR
Darien Williams: Scores in college debut
Sep 15th
Williams gathered in all three targets for 72 yards and one touchdown during Friday's 66-24 victory versus Colgate.
#6 WR
Emanuel Ross: Doesn't play in Week 3
Sep 12th
Ross (undisclosed) is out for the Week 3 game.
#5 RB
Malachi James: Out for Week 3, maybe longer
Sep 12th
James (undisclosed) is out for Friday's game against Colgate and could be out long-term, Brent Axe of The Syracuse Post-Standard reports.
#1 RB
Yasin Willis: Won't play Friday
Sep 11th
Willis will miss Friday's game versus Colgate with an undisclosed injury, Zak Wolf of The Daily Orange reports.
#1 WR
Johntay Cook: Efficient in OT win
Sep 7th
Cook (leg) hauled in all four targets for 27 yards during Saturday's 27-20 overtime victory over Connecticut.
Clem
Tigers News
#2 WR
Bryant Wesco: Another big day
Sep 15th
Wesco gathered in 7 of 8 targets for 126 yards and one touchdown during Saturday's 24-21 loss versus Georgia Tech.
#1 RB
Adam Randall: Scores again in loss
Sep 15th
Randall totaled 15 rushes for 80 yards and one touchdown during Saturday's 24-21 loss versus Georgia Tech.
#1 QB
Cade Klubnik: Struggles return in upset loss
Sep 15th
Klubnik completed 15 of 26 passes for 207 yards, one touchdown and one interception during Saturday's 24-21 loss against Georgia Tech. He also had 17 rushes for 62 yards with one touchdown.
#1 WR
Antonio Williams: Won't play in Week 3
Sep 12th
Williams (hamstring) is out for Saturday's game at Georgia Tech.
#2 RB
Jay Haynes: Out again Saturday
Sep 11th
Haynes (knee) won't play Saturday versus Georgia Tech, Jon Blau of The Charleston Post and Courier reports.
#6 RB
Peyton Streko: Ruled out
Sep 11th
Streko has been ruled out for Saturday's game against Georgia Tech, Jon Blau of The Charleston Post and Courier reports.