Clemson
24.5 Pts
Louisville
27.0 Pts
Friday November 14, 2025 at 7:30 PM ET
Loading Possible Bets...
Moneyline
DraftKings DraftKings
-130
PROBABILITY with vig removed
Clem Tigers Win (+110)
45.7%
Lou Cardinals Win (-130)
54.3%
LINE MOVEMENT
Spread
DraftKings DraftKings
-2.5
PROBABILITY with vig removed
Clem Win or Lose By < 3 Pts(-112)
50.4%
Lou Win By 3+ Pts(-108)
49.6%
LINE MOVEMENT
Over Under
DraftKings DraftKings
51.5
Points
PROBABILITY with vig removed
Over 52 Total Points(-105)
48.9%
Under 52 Total Points(-115)
51.1%
LINE MOVEMENT
Clem
Tigers Injury Report
Loading Tigers Injuries...
Lou
Cardinals Injury Report
Loading Cardinals Injuries
Clem
Tigers News
#2 WR
T.J. Moore: Quiet Saturday night
Nov 10th
Moore hauled in 3 of 4 targets for 37 yards during Saturday's 24-10 win against Florida State.
#1 WR
Antonio Williams: Scores vs. Florida State
Nov 10th
Williams hauled in all six targets for 62 yards and one touchdown during Saturday's 24-10 victory over Florida State.
#1 RB
Adam Randall: Rather quiet vs. 'Noles
Nov 10th
Randall tallied 15 rushes for 48 yards and hauled in their only target for 20 yards during Saturday's 24-10 victory versus Florida State.
#1 QB
Cade Klubnik: Scores by air and ground in win
Nov 10th
Klubnik completed 20 of 27 passes for 221 yards and one touchdown during Saturday's 24-10 victory versus Florida State. He also had eight rushes for one yard with one touchdown.
#2 RB
Gideon Davidson: Gets involved in narrow loss
Nov 3rd
Davidson posted 12 rushes for 51 yards and gathered in all four targets for 44 yards during Saturday's 46-45 loss versus Duke.
#3 WR
Tristan Smith: Announced as starter
Nov 1st
Smith is part of the Tigers' starting lineup for their upcoming game Saturday against Duke, Jon Blau of The Charleston Post and Courier reports.
#11 WR
Tristan Martinez: Cleared to return
Oct 30th
Martinez (undisclosed) is no longer listed on Clemson's injury report ahead of Saturday's game against Duke.
#6 RB
Peyton Streko: Off injury report
Oct 30th
Streko (undisclosed) has cleared Clemson's injury report ahead of Saturday's matchup with Duke.
Lou
Cardinals News
#1 RB
Isaac Brown: Remains out Friday
Nov 12th
Brown (lower leg) did not appear on the teams injury report but will still not play in Friday's game versus Clemson, Matt McGavic of SI.com reports.
#1 WR
Chris Bell: Suffering from poor QB play
Nov 10th
Bell notched six receptions (on 11 targets) for 49 yards during Saturday's 29-26 overtime defeat against California.
#2 WR
Caullin Lacy: Four grabs, 60 yards in loss
Nov 10th
Lacy reeled in 4 of 6 targets for 60 yards during Saturday's 29-26 overtime defeat versus California.
#2 RB
Keyjuan Brown: Another tremendous outing
Nov 10th
Brown totaled 14 rushes for 136 yards and hauled in 1 of 2 targets for five yards during Saturday's 29-26 overtime loss against California.
#1 QB
Miller Moss: Struggles continue vs. California
Nov 10th
Moss completed 20 of 38 passes for 203 yards and one interception during Saturday's 29-26 overtime defeat to California. He also had eight rushes for negative seven yards with one touchdown.
#3 RB
Duke Watson: Good to go Saturday
Nov 8th
Watson (undisclosed) is available for Saturday's game against California.
#6 WR
Kris Hughes: Good to go vs. Hokies
Oct 31st
Hughes (undisclosed) is good to go against Louisville.