Brandon Aiyuk headshot

Brandon Aiyuk Injury: Not ready to practice

Written by RotoWire Staff

Updated on November 3, 2025 at 8:12pm

San Francisco head coach Kyle Shanahan said that Aiyuk (knee) won't have his 21-day practice window opened this week, David Lombardi of SFStandard.com reports.

The 49ers are continuing to evaluate Aiyuk on a week-to-week basis as he moves through the rehab process for the right knee surgery he required after suffering ACL and MCL tears in an Oct. 20, 2024 game. While the 49ers are seemingly still hopeful that Aiyuk will contribute at some point this season, a more definitive target date for his 2025 debut won't become clear until he starts practicing.

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