The Saints are tougher on the boundary than in the slot, which should provoke a big game from Amon-Ra St. Brown.
The Indianapolis secondary is weakest on the boundary and downfield, where Mike Evans is at his best.
Drake London is due for a bounce-back after no catches in Week 1, but Jaire Alexander could deny it anyway.
The Colts' cornerback personnel is weak but their run defense is strong, setting up a feast for Calvin Ridley and the Jags passing game.