This article is part of our Fit or Miss series.
Injury news in soccer is notoriously sketchy, so while the below information should be used as a guide, always check the confirmed lineups before every match.
Last update: Friday, Aug. 21 at 2:00 p.m. EDT
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Providence Park
Friday, August 21 at 11:00 p.m. EDT
Portland Timbers
Out:Ben Zemanski (knee)
Probable:Fanendo Adi (hip)
Houston Dynamo
Doubtful:Ricardo Clark (hamstring), Taylor Hunter (knee), Jermaine Taylor (thigh)
Questionable:DaMarcus Beasley (undisclosed), Will Bruin (undisclosed), Alexander Lopez (undisclosed), Rob Lovejoy (hamstring), Raul Rodriguez (groin)
Probable:Giles Barnes (Achilles)
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BMO Field
Saturday, August 22 at 4:00 p.m. EDT
Toronto FC
Out:Mark Bloom (quad)
Doubtful:Damien Perquis (quad)
Probable:Luke Moore (ankle), Clement Simonin (knee)
Orlando City SC
Suspended:Darwin Ceren, Tyler Turner
Out:Conor Donovan (knee), Harrison Heath (kneecap), Kevin Molino (knee), Brek Shea (groin)
Doubtful:Tony Cascio (back)
Probable:Rafael Ramos (thigh)
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RFK Memorial Stadium
Saturday, August 22 at 7:00 p.m. EDT
D.C. United
Out:Fabian Espindola (knee), Chris Korb (knee)
Questionable:Nick DeLeon (hamstring)
San Jose Earthquakes
Out:Innocent (knee), Steven Lenhart (knee), Jordan Stewart (Achilles)
Doubtful:Michael Fucito (hamstring), Matias Perez Garcia (leg)
Questionable:Jean-Baptiste Pierazzi (foot)
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Mapfre Stadium
Saturday, August 22 at 7:30 p.m. EDT
Columbus Crew
Out:Sagi Lev-Ari (knee)
Doubtful:Sergio Campbell (calf), Gaston Sauro (match fitness)
Questionable:Emanuel Pogatetz (knee), Ben Swanson (hamstring)
Sporting Kansas City
Suspension:Benny Feilhaber
Out:Jalil Anibaba (quad), Roger Espinoza (foot), Ike Opara (Achilles)
Doubtful:Bernardo Anor (ankle), Seth Sinovic (concussion), Jordi Quintilla (match fitness)
Questionable:Soni Mustivar (groin)
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Stade Saputo
Saturday, August 22 at 8:00 p.m. EDT
Montreal Impact
Out:Kenny Cooper (knee), Cameron Porter (knee)
Doubtful:Hassoun Camara (knee), Adrian Lopez (knee)
Questionable:Ignacio Piatti (calf)
Probable:Didier Drogba (match fitness)
Philadelphia Union
Doubtful:Andrew Wenger (concussion)
Questionable:Maurice Edu (groin), Raymond Lee (thigh), Vincent Nogueira (quad), Brian Sylvestre (hand)
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Toyota Park
Saturday, August 22 at 8:30 p.m. EDT
Chicago Fire
Questionable:David Accam (hamstring), Gilberto (thigh), Shaun Maloney (possible transfer)
Colorado Rapids
Suspension:Sam Cronin
Questionable:Joe Greenspan (back), Lucas Pittinari (hamstring), James Riley (concussion), Luis Solignac (hamstring)
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Rio Tinto Stadium
Saturday, August 22 at 10:00 p.m. EDT
Real Salt Lake
Doubtful:Burrito (match fitness), Chris Schuler (knee)
Probable:Jordan Allen (hamstring), Joao Plata (hamstring)
Seattle Sounders
Out:Damion Lowe (hip)
Doubtful:Chad Barrett (hamstring), Andreas Ivanschitz (calf)
Questionable:Osvaldo Alonso (hamstring), Andy Craven (knee), Clint Dempsey (hamstring), Leonardo Gonzalez (hamstring), Marco Pappa (match fitness)
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BC Place Stadium
Saturday, August 22 at 10:00 p.m. EDT
Vancouver Whitecaps FC
Doubtful:Andre Lewis (knee), Ben McKendry (knee)
Questionable:Pa-Modou Kah (face), Diego Rodriguez (quad), Jordan Smith (match fitness)
FC Dallas
Doubtful:Mauro Diaz (quad), Stephen Keel (foot)
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StubHub Center
Sunday, August 23 at 3:00 p.m. EDT
Los Angeles Galaxy
Out:Brian Perk (ankle)
Doubtful:Todd Dunivant (calf)
Questionable:Baggio Husidic (calf), Jose Villareal (knee)
New York City FC
Out:Connor Brandt (hernia), George John (knee), Tony Taylor (knee)
Questionable:Mehdi Ballouchy (thigh), Javier Calle (hamstring), Frank Lampard (quad), Khiry Shelton (quad)