Manchester United are the biggest favorites on the slate, and Romelu Lukaku is surely to be highly owned in cash games and tournaments because of his goal-scoring odds.
Manchester United's Henrikh Mkhitaryan has scored double-digit fantasy points in six of his last seven starts, and the Red Devils will need him to be prolific if they want some points Sunday against Liverpool.
There aren't many elite goal-scorers on Monday's slate, despite high profile teams like Belgium and Italy, so it will be vital to find players who can contribute with other stats.
Arsenal may be eliminated from the title race, but a home match against Norwich easily puts Petr Cech on top of the goalkeeper rankings this week.
Matches against Crystal Palace and West Brom in the upcoming gameweek puts Alexis Sanchez near the top of the midfielder rankings.
Harry Kane has five goals in his last three Premier League matches, and a matchup against Liverpool this weekend puts him atop one of the positional rankings.
Fresh off a two-goal outing Sunday against Aston Villa, Harry Kane takes one of the top spots in this week's positional rankings thanks to a home matchup against Bournemouth.
A home match against Aston Villa is exactly what Manchester City could use after their recent slide, and the matchup makes Sergio Aguero a top play this weekend.
Despite a matchup against league-leaders Leicester City, Mesut Ozil garnered a first-place vote among midfielders, but was it enough to give him the top spot in the composite ranking?
Man City's attack may be a bit lighter without Kevin De Bruyne, but Sergio Aguero will still lead the charge this week against Sunderland's struggling defense.
Kevin De Bruyne has been a fantasy star this season, but one of his midfield teammates could provide more bang for the buck this weekend against West Ham.
After bagging a brace last weekend, Sergio Aguero finds himself at the top of the forward rankings this weekend. However, he's joined at the summit by the co-leader in goals scored this season.
A home match against the porous Sunderland defense vaults Tottenham's Harry Kane to the top of the forwards rankings this week.
Bakary Sako is back from his hamstring injury and could be a difference-maker in Crystal Palace's match against last-place Aston Villa on Tuesday.
Playing against an Everton defense that has struggled this season and will be without Seamus Coleman, Sergio Aguero takes the top spot in one of the positional rankings this week.
Mesut Ozil is one of the most expensive options on the board for Saturday's slate, but RotoWire's Alex Spalding has a number of value plays to fit the Arsenal midfielder into fantasy lineups.
Despite failing to score in three consecutive Premier League games, a home match against Bournemouth moves Jamie Vardy to the top of the forwards rankings.
With Real Madrid having already locked up the top spot in their group, manager Rafa Benitez may rest a number of his regular starters, which could answer the question of whether or not to fade Cristiano Ronaldo.