
The Manchester United attack sputtered last week, but they have a solid bounce-back opportunity in Gameweek 3 against Wolverhampton.

Harry Kane seems to be back in Tottenham's good graces, which should only help teammate Son Heung-Min this week against Watford.

The Chelsea set-piece situation continues to be cloudy, but RotoWire's Ryan Belongia explains why Mason Mount could be one of the top plays on Saturday's five-game Premier League slate on DraftKings.

Manchester United are missing a few key players, but RotoWire's Andrew Laird is still expecting Bruno Fernandes to have a big impact in Gameweek 1.

Liverpool open their 2021/22 Premier League campaign away to Norwich City, and RotoWire's Andrew Laird is expecting a dominant performance by the Reds.
![Premier League Projected Lineups: Gameweek 21 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/udp9cesf3l4v7dy0h5y3.jpg)
A number of injuries will alter lineups this weekend, with Son Heung-Min possible playing more centrally in place of the injured Harry Kane.
![Premier League Projected Lineups: Gameweek 20 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/zny8kjicgqkqvtglea1m.jpg)
Liverpool went with a heavily rotated side in their last Premier League match, but Mohamed Salah seems likely to start against Spurs this week after bagging a brace against Man United in the FA Cup on Sunday.
![Premier League Projected Lineups: Gameweek 19 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/zny8kjicgqkqvtglea1m.jpg)
With many teams playing twice in Gameweek 19, fantasy players will want to focus on double gameweek players.
![Premier League Projected Lineups: Gameweek 18 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/jmxmxlnl5qcopymddn56.jpg)
Despite a small break in Premier League action, plenty of teams had to deal with FA Cup matches, so rotation could continue to be an issue for the six-game Gameweek 18 slate.

Fantasy players should expect plenty of rotation due to the condensed holiday schedule, including the potential return of Sergio Aguero at the top of the Manchester City attack for Gameweek 16.

Manchester City are expected to take care of business against Southampton this weekend, which is why Kevin De Bruyne is near the top of Andrew Laird's weekly player rankings.

Harry Kane and Son Heung-Min continue to dominate all opponents, and RotoWire's Andrew Laird is expecting that to continue this weekend against Leicester City.

Leeds United scored five goals in their win over Newcastle on Wednesday, which could force Marcelo Bielsa to keep his same starting XI on Sunday against Manchester United.
![Fantrax Premier League Rankings: Gameweek 12 [Updated]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/gkn3ngjj0gkuvofrhzhr.jpg)
The Manchester Derby is the highlight match of Gameweek 12, and RotoWire's Andrew Laird is expecting Kevin De Bruyne to still have a big impact despite a tough matchup.
![Fantasy Premier League Rankings: Gameweek 12 [Updated]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/zny8kjicgqkqvtglea1m.jpg)
Mohamed Salah's spot in the starting XI isn't guaranteed after playing 90 minutes in the Champions League on Wednesday, but he ranks at the top of Andrew Laird's weekly rankings if he starts against Fulham.
![Premier League Projected Lineups: Gameweek 12 [Updated]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/jrbeihp2evjzoveaf0or.jpg)
After playing nearly the entire match against FC Midtjylland in the Champions League on Wednesday, Diogo Jota could move to the bench for this weekend's match against Fulham in favor of Roberto Firmino.
![Fantrax Premier League Rankings: Gameweek 11 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/bem6uk8md3uosk1yq97b.jpg)
Manchester United lost to Paris Saint-Germain in the Champions League on Wednesday, but they have a great opportunity to bounce back this weekend against West Ham.