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Four games will be played Wednesday, and the final one on the docket will be a pivotal matchup between Barcelona and Isaia Cordinier's Virtus Bologna club.
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Luka Mitrovic and Red Star host Valencia and help tip off both a five-game Tuesday and the latest double-game week.
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Five games will go off Thursday, and the action concludes with another rematch of last year's Final between Olympiacos and Sergio Rodriguez's Real Madrid club.
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The first day of action in Round 22 features five games, and one of them will be an all-German matchup between Sylvain Francisco's Bayern club and ALBA.
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Edmond Sumner and Zalgiris take on Barcelona and help bring an end to the busiest stretch of the season.
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Another Round tips off Thursday, and the action will begin with a matchup between Bayern and a Fenerbahce club featuring Tarik Biberovic.
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It will be a light Wednesday amid the latest double-game week, and the first of two games will involve Isaiah Canaan's Olympiacos club and Barcelona.
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A second straight double-game week begins in a busy way, as Juancho Hernangomez and Panathinaikos host Efes in one of the seven games on Tuesday's schedule.
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The Eternal Derby will go down again Thursday as Rokas Giedraitis and Red Star square off against Partizan in Stark Arena.
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The latest edition of El Clasico will take place Wednesday, and a Barcelona club led by Nicolas Laprovittola will be looking for a much-needed win against rival Real Madrid.
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A new year of EuroLeague play gets underway Tuesday, and a new era begins for Zalgiris, as Austin Hollins and co. move forward with a new coach.
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The first half of the regular season comes to a close Friday, and the final game on the docket will be a big-time matchup between Kemba Walker's Monaco club and Barcelona.
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A whopping seven games will be played Thursday, but there will be no shortage of eyeballs on Istanbul, where Shane Larkin and Efes are set to host Fenerbahce.
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It will be a busy Friday in the EuroLeague, and in the fourth of the six scheduled contests Malte Delow and ALBA will face off against Fenerbahce.