San Francisco 49ers vs Seattle Seahawks Odds, Week 18, 2025

#1 TE

George Kittle: Trending in right direction

Dec 31st

San Francisco general manager John Lynch said Wednesday that Kittle (ankle) is trending in the right direction to suit up Saturday night versus the Seahawks, Cam Inman of The San Jose Mercury News reports.

#1 RB

Christian McCaffrey: Trending to play Saturday

Dec 31st

San Francisco general manager John Lynch said Wednesday that McCaffrey (back) is trending in the right direction to play Saturday against the Seahawks, Cam Inman of The San Jose Mercury News reports.

#3 RB

Jordan James: No run on offense in Week 17

Dec 31st

James played just two snaps -- both on special teams -- in Sunday's 42-38 win over the Bears.

#5 WR

Skyy Moore: Notches first down on rush

Dec 31st

Moore carried once for 10 yards and brought back two punts for 11 yards and four kickoffs for 92 yards in Sunday's 42-38 win over the Bears.

#7 WR

Jacob Cowing: Practice window could open soon

Dec 31st

San Francisco head coach Kyle Shanahan said Friday that Cowing (hamstring) could have his 21-day practice window opened during Week 18 prep, Matt Barrows of The Athletic reports.

#3 LDE

Keion White: Doesn't practice Tuesday

Dec 30th

White (groin) did not participate in Tuesday's practice, Nick Wagoner of ESPN.com reports.

#1 LCB

Renardo Green: No limitations Tuesday

Dec 30th

Green (neck) is expected to be listed as a full participant at practice Tuesday, Nick Wagoner of ESPN.com reports.

#1 FB

Kyle Juszczyk: Working through hip injury

Dec 30th

Juszczyk didn't participate in Tuesday's practice due to a hip injury, Nick Wagoner of ESPN.com reports.

#1 LT

Trent Williams: Not practicing Tuesday

Dec 30th

Williams (hamstring) won't participate in practice Tuesday, Nick Wagoner of ESPN.com reports.

#2 LDE

Yetur Gross-Matos: Working through knee issue

Dec 30th

Gross-Matos (knee) was a limited participant in Tuesday's practice, Noah Furtado of the San Francisco Chronicle reports.

#1 SCB

Upton Stout: Limited to open Week 18 prep

Dec 30th

Stout (concussion) was a limited participant in Tuesday's practice, Matt Barrows of The Athletic reports.

#2 WR

Ricky Pearsall: Starts week with limited practice

Dec 30th

Pearsall (knee/ankle) will be a limited participant in Tuesday's practice, Matt Barrows of The Athletic reports.

#1 FS

Malik Mustapha: Tallies three tackles vs. Chicago

Dec 29th

Mustapha registered three tackles (two solo) and one pass defense during San Francisco's 42-38 win over Chicago on Sunday.

#1 SS

Ji'Ayir Brown: Tallies four stops in Week 17 win

Dec 29th

Brown registered four tackles (one solo) and one pass defense during the 49ers' 42-38 win over the Bears on Sunday.

#1 MLB

Tatum Bethune: Game-high 11 stops vs. Chicago

Dec 29th

Bethune logged 11 tackles (seven solo), including one stop for a loss, and one pass defense during the 49ers' 42-38 win over the Bears on Sunday.

#3 QB

Kurtis Rourke: Officially out for 2025

Dec 29th

Rourke (knee) will remain on the 49ers' reserve/non-football injury list for the rest of the 2025 season, Matt Maiocco of NBC Sports Bay Area reports.

#3 TE

Luke Farrell: No targets sans Kittle in Week 17

Dec 29th

Farrell logged 27 snaps on offense and wasn't targeted in Sunday's 42-38 win over the Bears.

#4 WR

Kendrick Bourne: Gains 25 yards off one reception

Dec 29th

Bourne caught his only target for 25 yards in Sunday's 42-38 win over the Bears.

#3 WR

Demarcus Robinson: Grabs two receptions Sunday

Dec 29th

Robinson caught both of his targets for 30 yards in Sunday's 42-38 win over the Bears.

#2 RB

Brian Robinson: Garners five touches Sunday

Dec 29th

Robinson took four carries for 22 yards and grabbed his only target for six yards in Sunday's 42-38 win over Chicago.

#1 WR

Jauan Jennings: Extends TD streak to five games

Dec 28th

Jennings had two receptions on four targets for 42 yards and a touchdown in Sunday's 42-38 victory over Chicago.

#2 TE

Jake Tonges: Cashes in on prime opportunity

Dec 28th

Tonges corralled seven of nine targets for 60 yards and a touchdown in Sunday's 42-38 win over the Bears.

#1 QB

Brock Purdy: Another five-TD performance

Dec 28th

Purdy completed 24 of 33 pass attempts for 303 yards, three touchdowns and one interception while taking six carries for 28 yards and two touchdowns in Sunday's 42-38 win over Chicago.

#1 K

Eddy Pineiro: Makes all six PATs in win

Dec 28th

Pineiro didn't attempt a field goal in Sunday's 42-38 win over the Bears but converted all six of his extra-point tries.

#2 MLB

Curtis Robinson: Healthy scratch for SNF

Dec 28th

Robinson (coach's decision) is inactive for Sunday night's contest against the Bears.

#4 RB

Isaac Guerendo: Healthy scratch again in Week 17

Dec 28th

Guerendo (coach's decision) is inactive for Sunday's game against Chicago.

#6 WR

Jordan Watkins: Inactive in Week 17

Dec 28th

Watkins (coach's decision) is inactive for Sunday's game against the Bears.

#4 MLB

Fred Warner: Could return during playoffs

Dec 27th

Warner (ankle) is ahead of schedule in his recovery and could be a candidate to return to action if the 49ers make a deep playoff run, Ian Rapoport and Mike Garafolo of NFL Network report.

#1 WLB

Dee Winters: Seals win with pick-six

Dec 23rd

Winters logged three tackles (one solo) and two defensed passes, including an interception that he returned for a touchdown, in Monday's 48-27 victory versus the Colts.

#1 LG

Spencer Burford: Ready for MNF

Dec 20th

Burford (ankle) doesn't have an injury designation ahead of Monday night's game against the Colts.

#2 DT2

Jordan Elliott: Ready for Week 16

Dec 20th

Elliott (knee) does not carry an injury designation for Monday's game against the Colts.

#1 RDE

Sam Okuayinonu: Ready to face Colts

Dec 20th

Okuayinonu (ankle) does not carry an injury designation for Monday's game against Indianapolis.

#2 WLB

Nick Martin: Lands on IR

Dec 20th

The 49ers placed Martin (concussion) on injured reserve Saturday.