Ryan Mathews is getting healthy, but he's not likely to play in the first couple weeks, leaving Ronnie Brown to lead the San Diego backfield.
LeGarrette Blount looks to have lost the starting running back job in Tampa Bay as he was relegated to backup duty in the last exhibition game.
Matt Forte is the No. 1 back in Chicago, but Michael Bush's emergence could relegate Forte to the sideline when the team is at the goal line.
Neither quarterback has looked great this preseason, but John Skelton might have the early edge on Kevin Kolb to be Arizona's starter.
Jahvid Best and Mikel Leshoure are battling to start at running back in Detroit, but the job might come down to who can stay healthy.
Colt McCoy could do more standing than playing this season if he doesn't win his battle with rookie Brandon Weeden for the starting QB job in Cleveland.
Ryan Williams' injury means for the first time little competition remains for Chris Wells in Arizona.
Chris Wells is a great talent, but he's headed for a camp competition with rookie Ryan Williams. Here's an early look at job battles across the NFL.