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The Chiefs might assign star corner Trent McDuffie to A.J. Brown, but if so they risk setting loose DeVonta Smith against Kansas City's more modest corners.
The 2025 Senior Bowl has plenty of fantasy football rookies to put on your dynasty draft radar. Mario Puig breaks down the 47 Senior Bowl standouts to monitor this draft season.
Amon-Ra St. Brown against Noah Igbinoghene could prove to be a problem for Washington's defense.
Justin Jefferson is the better player, but Puka Nacua was targeted on 23.0 percent of his snaps in 2024 while Jefferson was targeted on only 15.7 percent of his.
The Texans insist on playing safeties in the slot, which might be a way of asking for trouble from Ladd McConkey.
When the Lions need to score quickly they look to Jameson Williams, and the Lions might need to score quickly in a Sunday night shootout.
Justin Jefferson looks truly unstoppable in a game where the Vikings need points and the Lions probably can't cover.
Monday's game could be a shootout as the 49ers' rugged wideout duo faces off against Detroit's lightweight backup cornerbacks.
Drake London and Darnell Mooney could have faced a tough matchup Monday, but the absence of CB1 Marshon Lattimore helps Atlanta's passing projection.
No NFC team wants to see the rampaging Eagles in the playoffs, and A.J. Brown is arguably the top fantasy receiver for the postseason.
Michael Pittman could be a challenging cover for the Giants' shorter and light cornerbacks.
Kendre Miller might be a massive road underdog, but he still could be a good single-game slate pick against Green Bay on Monday.
CeeDee Lamb could be a problem for Tampa Bay's heavy-footed cornerbacks.
Michael Penix is unproven, but the quarterback change gives new hope to Falcons pass catchers like Drake London.
Justin Jefferson is still king, but Jordan Addison's emergence has made it more difficult to afford both star Vikings wideouts in a single lineup.
The Falcons offense figures to get on track Monday, and as the engine of that offense Bijan Robinson projects very well against Las Vegas.
The Packers are down their top two corners Sunday, setting the Seahawks passing game up for a strong showing.
Ever since Marshon Lattimore switched teams, Washington's Week 15 matchup with New Orleans became a good matchup for Terry McLaurin.
The strength of the Bengals is their passing attack, but running back Chase Brown could be the team's leading producer from scrimmage Monday.
DeAndre Hopkins is the key to the Chiefs passing game, but his playing time projection is uncertain due to Kansas City's wideout rotation.
Now that he's off the injury report, Mike Evans should be set up for a strong game against Las Vegas.
David Njoku could see a big target count, especially if Patrick Surtain denies targets to wideout Jerry Jeudy.
The Bills should have at least one productive running back Sunday, and James Cook has scored touchdowns at a rapid rate in 2024.
Terry McLaurin should stay hot against a Titans defense starting its third- and fourth-string corners on the boundary.
Isiah Pacheco makes his return Friday, but it's not clear how much usage he'll get in his first game back.
There's a chance DJ Moore maintains his momentum against a Detroit secondary without Carlton Davis on Thursday.
Justin Herbert could post productive fantasy numbers Monday, especially if he keeps running as often as he has in the past month.
The Eagles need to get A.J. Brown the ball Sunday night, and there might not be much the Rams can do to slow him.
The Buccaneers need to get the ball to Mike Evans, and it's not obvious what the Giants defense can do to stop it.
At 6-4 the Texans might need to fully unleash Nico Collins in his first game back, because they can't afford to take a fifth loss at the hands of Dallas.
The Chargers might not throw much by design, but if the Bengals offense scores quickly then Ladd McConkey might be busy as the Chargers try to keep pace.
The Ravens might want to shadow George Pickens with Marlon Humphrey, because the other Ravens corners can't cover Pickens.
Kyren Williams is likely in line for a big game against a weak Miami run defense.
Amon-Ra St. Brown could be productive against a Houston defense that doesn't move around its corners, allowing Detroit to avoid Derek Stingley.
Deebo Samuel could go nuts as the desperate 49ers take aim at a weak Tampa Bay corner rotation.
Baker Mayfield has thrown seven interceptions in his last three games, and without his top two wideouts he could throw a few more interceptions at Arrowhead on Monday.
Michael Pittman has struggled through a back injury, but if the injury has improved then Pittman could get back on track with Joe Flacco at quarterback.
Justin Jefferson will almost certainly have a big game Sunday, and the Colts pass defense is weak enough for Jordan Addison to get rolling in the same game.
The arrival of Russell Wilson lifts up the Pittsburgh passing game, but it also makes life easier for Najee Harris, who could keep rolling Monday.
The 49ers need Jordan Mason to carry the offense Sunday, and he's likely prepared to do so.
With Tua Tagovailoa back in the lineup Jaylen Waddle should get rolling against Arizona, and the same is true of Tyreek Hill if he plays through his foot injury.
The Cardinals must get the ball to Marvin Harrison more, and the Chargers' beat-up corner rotation might provide a get-right game Monday.
Secondary Ravens pass catchers like Rashod Bateman might get open against Tampa Bay's weak cornerback rotation.
The Steelers hope Russell Wilson can improve the Pittsburgh passing game, but the fading veteran steps into a challenging situation Sunday night.
Drake London's breakout should continue against a Seattle secondary that might be without its two starting boundary corners.
If the Jets really mean to commit to the ground game then they'll have to prove it by feeding Breece Hall against the Bills on Monday.
Tyrone Tracy showed up big for the Giants in Week 5, and they'll need to call on him again with Devin Singletary (groin) unavailable against Cincinnati on Sunday night.
The showdown between Detroit and Dallas could set up a punch-for-punch heavyweight contest where CeeDee Lamb and Amon-Ra St. Brown both go off.
Derek Carr has a career average of just 6.3 yards per pass against the Chiefs, and now he needs to play at Arrowhead with an interior offensive line decimated by injury.
Dak Prescott is without Brandin Cooks against a dangerous Pittsburgh defense, but he should need to throw the ball often given Dallas' rushing struggles.