Jerry Donabedian expects big things from Baker Mayfield and Bucky Irving against the Panthers on Sunday, while Tu Tagovailoa and D'Andre Swift get much tougher matchups on Thanksgiving.
Justin Jefferson will almost certainly have a big game Sunday, and the Colts pass defense is weak enough for Jordan Addison to get rolling in the same game.
Drake London's breakout should continue against a Seattle secondary that might be without its two starting boundary corners.
Amon-Ra St. Brown will likely torch a thin Buccaneers secondary playing without its star enforcer in Antoine Winfield.
There's a lot to keep track of as the Eagles face the Packers, but the headlining stories might be star free agent RB pickups Saquon Barkley and Josh Jacobs.
Mike Evans has to slow down eventually, but probably not against Washington's undersized boundary corners.
Nico Collins could see an enormous target share with the Texans managing multiple wideout injuries.
CeeDee Lamb could have one of his biggest games playing against a Lions defense that's tougher against the run than the pass.
DK Metcalf could pose a major big-play threat to Tennessee's injury-challenged corner rotation.
A three-round mock that considers rebuild scenarios where Chicago trades Justin Fields and San Francisco trades Trey Lance.