Best Anytime Touchdown Scorer Prop Bets Week 13: NFL Player Prop Predictions

The NFL Week 13 odds are out and, as always, I'm here to break down the best anytime touchdown bets on the slate. Just make sure you're maximizing each prop by taking advantage of offers like the bet365 bonus code. 

I've looked at every major sportsbook and found the best line for each of my anytime touchdown picks. Here are my four best anytime touchdown props for Week 13.  

• Note: This article won't feature any Thursday games, as I covered those in my best anytime TD Bets for 2025 Thanksgiving Games story. 

Best DraftKings Anytime TD Prop Bets for Week 13

All odds in this section were sourced from DraftKings Sportsbook. Be sure to use a DraftKings Sportsbook promo to maximize your player prop bets.

James Cook Anytime Touchdown (-110) 

I have a hard time seeing Pittsburgh keeping James Cook out of the end zone. Cook is averaging a career-best 98.5 rushing yards per game this season, scoring at least one TD in seven of his 11 appearances. His eight rushing TDs are tied for the sixth-best mark in football. Now he gets to face the Steelers, who are the league's sixth-worst run defense in EPA. Pittsburgh has allowed a rushing TD in two of its last three games, and Cook has scored a touchdown in back-to-back games. This is a great value at close to even odds. 

TreVeyon Henderson Anytime Touchdown (-130)  

The Patriots' offensive line is as banged up as it gets, which should theoretically limit the run game. But they're facing the one team in the league that might not be able to exploit that. The New York Giants are the worst run defense in football, allowing 0.193 rushing EPA per play. That's more than twice as bad as the second-worst team in that regard, the Bills (0.078). And NYG is particularly bad at limiting explosive runs, allowing the most carries of 20-plus yards (15) and 40-plus yards (6). Even with a banged-up offensive line, that feels like a death sentence against TreVeyon Henderson, who looks like one of the most explosive backs in football. Henderson has recorded five touchdowns over his last three games, and I think he'll break a few big plays on Monday Night Football. 

If you're hunting for a huge payout, he's the my favorite multi-TD value on the slate. Henderson is +500 to score twice and +3000 to score three times at FanDuel Sportsbook. 

Best FanDuel Anytime TD Prop Bets for Week 13

All odds in this section were sourced from FanDuel Sportsbook. Be sure to use a FanDuel Sportsbook promo to maximize your player prop bets. 

Dalton Schultz Anytime Touchdown (+240) 

After adding Sauce Gardner, there aren't a lot of holes on this Colts' defense. But you can beat them with a good pass-catching tight end. Indianapolis surrenders 72.2 receiving yards per game to opposing tight ends, which is the second-worst mark in the league. Dalton Schultz has only scored once this season, but he should get some extra looks this week against Indianapolis. At greater than 2-to-1 odds, Schultz looks like one of the best flyers on the board. 

Jaylen Waddle Anytime Touchdown (+110) 

De'Von Achane has been a mainstay in this article in 2025. And he's almost always delivered, scoring at least once in seven of 11 games. As much as it pains me to say it, everything I'm seeing tells me to stay away from him this weekend. New Orleans is a top-six run defense in EPA, and the Saints allow the sixth-fewest receiving yards to opposing RBs to boot. If Achane is bottled up, expect Jaylen Waddle to be the focal point for Miami. 

The Saints are great against the run, but they're a bottom-10 unit in pass defense EPA. And Waddle has really come on lately, averaging 79.3 receiving yards per game over his last four – up from 57.9 per game over his first seven. The Dolphins' WR1 has found the end zone twice over his last four games. At plus odds, he's a great value to score in Week 13. 

Maximize Week 13 Props With OddsJam

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Where to Bet on Anytime Touchdown Props

Below, I've provided a list of the top sportsbooks that offer anytime touchdown betting markets. I've also provided the sign-up bonus at each book, so you can make the most of your prop bets.