Ajax are sizable underdogs for Tuesday's trip to Liverpool, but RotoWire's Chris Owen isn't afraid to target players like Dusan Tadic, as none of them will be overly popular in a tough matchup.
Liverpool's full-backs are underpriced for Tuesday's five-game slate at DraftKings and RotoWire's Ryan Belongia is inclined to use both Trent Alexander-Arnold and Kostas Tsikmas against Ajax.
Switzerland are firmly favored against Wales on Sunday, which is why RotoWire's Adam Zdroik is expecting Ricardo Rodriguez to be very popular in cash games.
Italy are favored at home against Switzerland on Wednesday, and RotoWire's Adam Zdroik is expecting Lorenzo Insigne to be one of the most popular players in cash games and GPPs.
RotoWire's Ben Novack breaks down and tracks all the expected set-piece and penalty takers for each team participating in UEFA EURO 2021.
Italy are favored against Turkey in the UEFA EURO 2020 opener Friday, and RotoWire's Adam Zdroik is expecting plenty of Italian stacks in cash games and GPPs on DraftKings.
Turkey and Italy kick off the UEFA Euro 2020 tournament Friday in Rome, where the Italians are firmly favored.
James Maddison has made the score-sheet in five of his last six starts, and RotoWire's Andrew Laird thinks he's one of the 10 best players on Fantrax for Gameweek 22.
Trent Alexander-Arnold is in solid form, and a matchup against Brighton this week has him as one of the top defenders in Andrew Laird's weekly player rankings.
Pierre-Emerick Aubameyang returned to full training Monday, which could allow him to start Tuesday against Wolverhampton.
![Fantrax Premier League Rankings: Gameweek 21 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/zny8kjicgqkqvtglea1m.jpg)
He hasn't scored in five consecutive Premier League starts, but RotoWire's Andrew Laird is expecting Mohamed Salah to have a big impact this weekend against West Ham.
![Fantasy Premier League Rankings: Gameweek 21 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/i2zozp4966baokt30byh.jpg)
While he didn't get on the score-sheet in Manchester City's 5-0 win over West Brom this week, RotoWire's Andrew Laird is expecting Phil Foden to make a major impact this weekend against Sheffield United.
![Premier League Projected Lineups: Gameweek 21 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/udp9cesf3l4v7dy0h5y3.jpg)
A number of injuries will alter lineups this weekend, with Son Heung-Min possible playing more centrally in place of the injured Harry Kane.
![Fantrax Premier League Rankings: Gameweek 19 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/z2i4rgud9xnlxer9uytk.jpg)
Even though he has a tough matchup against Manchester City, RotoWire's Andrew Laird still thinks Jack Grealish of Aston Villa will be one of the top players in Gameweek 19.
![Fantasy Premier League Rankings: Gameweek 19 [UPDATED]](https://res.cloudinary.com/rotowire/image/upload/ar_16:6,c_fill,dpr_auto,f_auto,g_auto:custom_no_override,q_auto,w_auto/jmxmxlnl5qcopymddn56.jpg)
Manchester City will line up against Crystal Palace and Aston Villa in Gameweek 19, which should have plenty of fantasy players excited about Kevin De Bruyne's upside if he plays both matches.
With many teams playing twice in Gameweek 19, fantasy players will want to focus on double gameweek players.
Dominic Calvert-Lewin has struggled a bit recently, but he'll get a boost this week as Richarlison is expected to return to the starting XI for Friday's match against West Ham.
Fantasy players should expect plenty of rotation due to the condensed holiday schedule, including the potential return of Sergio Aguero at the top of the Manchester City attack for Gameweek 16.