San Francisco 49ers vs Arizona Cardinals Odds, Week 3, 2025

#2 FS

Siran Neal: Enters concussion protocol

Sep 15th

Neal has entered the league's concussion protocol following the 49ers' Week 2 win over the Saints, Nick Wagoner of ESPN.com reports.

#1 LG

Ben Bartch: Dealing with ankle sprain

Sep 15th

Bartch suffered a high-ankle sprain during Sunday's 26-21 win over the Saints, Nick Wagoner of ESPN.com reports.

#2 LT

Spencer Burford: Dealing with knee injury

Sep 15th

Burford suffered a knee injury in Sunday's 26-21 win over the Saints, David Lombardi of SFStandard.com reports.

#1 WR

Jauan Jennings: Day-to-day with ankle issue

Sep 15th

San Francisco head coach Kyle Shanahan said Monday that Jennings came out of Sunday's 26-21 win over the Saints with an ankle injury, Jennifer Lee Chan of NBC Sports Bay Area reports.

#1 K

Eddy Pineiro: Misses PAT in Niners debut

Sep 15th

Pineiro went 2-for-3 on extra-point attempts and made both of his field-goal tries during the 49ers' 26-21 win over the Saints on Sunday.

#4 WR

Marquez Valdes-Scantling: Logs nine snaps on offense

Sep 15th

Valdes-Scantling failed to bring in his only target in Sunday's 26-21 win over the Saints.

#1 TE

Jake Tonges: Nabs four receptions Sunday

Sep 15th

Tonges finished with four receptions (on five targets) for 31 yards in Sunday's 26-21 win over the Saints.

#2 TE

Luke Farrell: Scores first TD of career

Sep 15th

Farrell brought in two of three targets for 15 yards and a touchdown in Sunday's 26-21 win over the Saints.

#1 MLB

Fred Warner: Does it all vs. Saints

Sep 15th

Warner recorded 11 total tackles (seven solo), one pass defended, one forced fumble and one fumble recovery in Sunday's 26-21 win over the Saints.

#3 RB

Isaac Guerendo: No carries in Week 2 win

Sep 15th

Guerendo returned two kickoffs for 47 yards and was not used on offense in Sunday's 26-21 win over the Saints.

#1 RDE

Nick Bosa: Productive again in Week 2

Sep 15th

Bosa recorded nine total tackles (three solo), including 1.0 sacks, during Sunday's 26-21 win over the Saints.

#2 RB

Brian Robinson: Handles seven touches Sunday

Sep 15th

Robinson rushed six times for 20 yards and caught his only target for a loss of one yard in Sunday's 26-21 win over New Orleans.

#3 WR

Kendrick Bourne: Three catches in return to Niners

Sep 14th

Bourne caught all three of his targets for 32 yards in Sunday's 26-21 win over the Saints.

#2 WR

Ricky Pearsall: Four grabs in Week 2 win

Sep 14th

Pearsall caught four of six targets for 56 yards in Sunday's 26-21 win over the Saints. He also rushed once for minus-4 yards.

#2 QB

Mac Jones: Tosses three TDs in win

Sep 14th

Jones completed 26 of 39 passes for 279 yards and three touchdowns in Sunday's 26-21 win over the Saints. He added six rushing yards on six carries.

#1 RB

Christian McCaffrey: Finds end zone in Week 2 win

Sep 14th

McCaffrey carried the ball 13 times for 55 yards and caught six of seven targets for 52 yards and a touchdown in Sunday's 26-21 win over the Saints.

#1 FB

Kyle Juszczyk: Won't return vs. New Orleans

Sep 14th

Juszczyk has been ruled out for the rest of Sunday's game against the Saints due to a concussion, Jennifer Lee Chan of NBC Sports Bay Area reports.

#4 RB

Jordan James: Healthy scratch vs. NOLA

Sep 14th

James (coach's decision) is inactive for Sunday's game against the Saints, Briana Jeannel of the 49ers' official site reports.

#1 LT

Trent Williams: Suiting up Sunday

Sep 14th

Williams (knee) is active for Sunday's matchup with the Saints, Briana Jeannel of the 49ers' official site reports.

#6 WR

Jordan Watkins: Pro debut pushed back

Sep 14th

Watkins (coach's decision) is inactive for Sunday's game at New Orleans, Briana Jeannel of the 49ers' official site reports.

#1 QB

Brock Purdy: Unlikely to return for Week 3

Sep 14th

Purdy (toe/shoulder), who has been ruled out for Sunday's game in New Orleans, is considered unlikely to be available for the 49ers' Week 3 game versus the Cardinals, though his condition has improved over the past week, Adam Schefter of ESPN reports. "We'll see for next week," one source told Schefter, regarding Purdy's status. "Next week will be tight, but he progressed a lot this week."

#2 LDE

Yetur Gross-Matos: Returns to practice Thursday

Sep 11th

Gross-Matos (knee) was a limited participant in Thursday's practice, Vic Tafur of The Athletic reports.

#3 TE

George Kittle: Move to IR official

Sep 9th

The 49ers placed Kittle (hamstring) on injured reserve Tuesday.

#5 WR

Skyy Moore: Handles return duties for SF

Sep 8th

Moore did not receive a target and returned five combined kicks for 63 yards in Sunday's 17-13 win over Seattle.

#1 RT

Colton McKivitz: Inks extension with San Francisco

Sep 8th

McKivitz signed a three-year, $45 million extension with the 49ers on Monday, Adam Schefter of ESPN reports.

#1 SS

Marques Sigle: Gets starting nod Week 1

Sep 7th

Sigle will be the 49ers' starting safety against the Seahawks on Sunday, Matt Maiocco of NBC Sports Bay Area reports.

#1 RG

Dominick Puni: Ready to face Seahawks

Sep 5th

Puni (knee) does not have an injury designation ahead of Sunday's game against the Seahawks, Michael-Shawn Dugar of The Athletic reports.

#2 RDE

Sam Okuayinonu: Logs full practice Wednesday

Sep 3rd

Okuayinonu (shoulder) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#2 DT2

CJ West: Logs full practice Wednesday

Sep 3rd

West (knee) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#1 SCB

Upton Stout: Recovered from calf injury

Sep 3rd

Stout (calf) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#1 LDE

Mykel Williams: Full participant in practice

Sep 3rd

Williams (knee) practiced in full Wednesday, Cam Inman of The San Jose Mercury News reports.

#1 FS

Jason Pinnock: Logs full practice

Sep 3rd

Pinnock (heel) was a full participant in Wednesday's practice, Cam Inman of The San Jose Mercury News reports.

#1 RCB

Deommodore Lenoir: Recovered from hip injury

Sep 3rd

Lenoir (hip) was not listed on the 49er's injury report Wednesday, Cam Inman of The San Jose Mercury News reports.