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Cardinals vs Jaguars Odds, Lines, Spreads & Totals 2025

Jaguars
25.0 Pts
Cardinals
22.5 Pts
Sunday November 23, 2025 at 4:05 PM ET
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JAX
Jaguars Injury Report
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JAX
Jaguars Lineup
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Cardinals Lineup
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JAX
Jaguars News
#5 WR
Dyami Brown: Non-factor against Chargers
Nov 18th
Brown failed to secure his only target in Sunday's 35-6 win over the Chargers.
#1 LOLB
Foyesade Oluokun: Logs five stops vs. Bolts
Nov 17th
Oluokun recorded five total tackles (three solo) and two passes defensed in Sunday's 35-6 win over the Chargers.
#3 TE
Johnny Mundt: Notches two receptions
Nov 17th
Mundt caught two of three targets for 25 yards during Sunday's 35-6 win against the Chargers.
#2 TE
Quintin Morris: Catches first pass of 2025
Nov 17th
Morris secured one of three targets for 11 yards during Sunday's 35-6 win against the Chargers.
#3 WR
Parker Washington: Targeted twice in blowout win
Nov 17th
Washington caught both his targets for 20 yards during Sunday's 35-6 win against the Chargers.
#3 RB
LeQuint Allen: Garners eight garbage-time carries
Nov 17th
Allen rushed eight times for 36 yards and returned two kickoffs for 55 yards during Sunday's 35-6 win against the Chargers.
#1 K
Cam Little: Makes five PATs in win
Nov 16th
Little did not attempt a field goal and went 5-for-5 on PATs in Sunday's 35-6 win over the Chargers.
#1 QB
Trevor Lawrence: Posts two total TDs in win
Nov 16th
Lawrence completed 14 of 22 passes for 153 yards with a touchdown and an interception while rushing five times for nine yards and another score in the Jaguars' 35-6 win over the Chargers on Sunday.
#1 RB
Travis Etienne: Pair of rush TDs in win
Nov 16th
Etienne rushed 19 times for 73 yards and two touchdowns and failed to bring in either of his two targets in the Jaguars' 35-6 win over the Chargers on Sunday.
#2 WR
Jakobi Meyers: Leads Jags wideouts in Week 11 win
Nov 16th
Meyers caught five passes (on six targets) for 64 yards during the Jaguars' 35-6 win over the Chargers on Sunday.
#4 WR
Tim Patrick: Hauls in one-yard TD pass
Nov 16th
Patrick finished Sunday's 35-6 win over the Chargers with three catches (on four targets) for 20 yards and a touchdown.
#2 RB
Bhayshul Tuten: Hurts ankle Sunday
Nov 16th
Tuten was forced out of Sunday's game against the Chargers with an ankle injury.
#1 RCB
Greg Newsome: Won't return Sunday
Nov 16th
Newsome (ankle) has been ruled out for the rest of Sunday's game against the Chargers, John Shipley of SI.com reports.
#1 RDE
Travon Walker: Questionable to return in Week 11
Nov 16th
Walker is dealing with a knee issue and is questionable to return to Sunday's matchup against the Chargers, John Oehser of the Jaguars' official site reports.
#4 RB
Cody Schrader: Healthy scratch
Nov 16th
Scrader (coach's decision) is inactive for Sunday's game against the Chargers.
#1 WR
Brian Thomas: Sitting out second straight game
Nov 16th
Thomas (ankle) is inactive for Sunday's game against the Chargers.
#2 LCB
Travis Hunter: Set to remain two-way player in '26
Nov 16th
The Jaguars plan to continue utilizing Hunter (knee) as their top wide receiver and as a matchup cornerback in 2026, Ian Rapoport of NFL Network reports.
#1 LG
Ezra Cleveland: Set to return Week 11
Nov 14th
Cleveland (knee) does not have an injury designation for Sunday's game against the Chargers.
#1 SCB
Jourdan Lewis: Ruled out for Sunday
Nov 14th
Lewis (neck) has been ruled out ahead of Sunday's game against the Chargers, Demetrius Harvey of The Florida Times-Union reports.
#1 RT
Anton Harrison: Ruled out
Nov 14th
Harrison (knee/ankle) has been ruled out ahead of Sunday's matchup against the Chargers, Demetrius Harvey of The Florida Times-Union reports.
#1 ROLB
Dennis Gardeck: Good to go Sunday
Nov 14th
Gardeck (chest) has no injury designation ahead of Sunday's matchup against the Chargers.
#1 TE
Hunter Long: To miss Sunday's game
Nov 14th
Long (hip/knee) has been ruled out for Sunday's game versus the Chargers.
#4 TE
Brenton Strange: Won't return Sunday
Nov 14th
Strange (hip) has been ruled out for Sunday's game against the Chargers.
#1 SS
Antonio Johnson: Makes impact in Week 10 loss
Nov 11th
Johnson recorded six tackles (three solo), including 1.0 sacks, and a defensed pass in Sunday's loss to Houston.
#1 LCB
Jarrian Jones: Nabs pickoff in Week 10 loss
Nov 11th
Jones registered four tackles (all solo) and two defensed passes, including an interception, in Sunday's loss to the Texans.
#1 MLB
Devin Lloyd: Racks up eight stops in Week 10
Nov 11th
Lloyd finished Sunday's loss to the Texans with eight tackles (two solo).
#1 FS
Andrew Wingard: Ties for team lead in stops Sunday
Nov 11th
Wingard tallied nine tackles (three solo) and a defensed pass in Sunday's Week 10 loss to Houston.
#6 WR
Austin Trammell: Secures first catches of 2025
Nov 10th
Trammell caught two of three targets for 33 yards during Sunday's 36-29 loss to the Texans.
#1 LDT
DaVon Hamilton: Dealing with back injury
Nov 5th
Hamilton (back) was limited in Wednesday's practice.
#2 SCB
Montaric Brown: First INT of season in win
Nov 4th
Brown recorded five tackles (four solo) and one interception in the Jaguars' win over the Raiders on Sunday.
ARI
Cardinals News
#4 WR
Xavier Weaver: Minimal production against 49ers
Nov 18th
Weaver caught two of three targets for 15 yards in Sunday's 41-22 loss to the 49ers.
#2 TE
Elijah Higgins: Two grabs in loss
Nov 18th
Higgins caught two of three targets for 11 yards in Sunday's 41-22 loss to the 49ers.
#2 RB
Emari Demercado: Likely out with high-ankle sprain
Nov 18th
Demercado sustained a high-ankle sprain in Sunday's 41-22 loss to the 49ers and is unlikely to be available for the Cardinals' Week 12 game against the Jaguars, Adam Schefter of ESPN reports.
#1 FS
Budda Baker: Posts eight stops vs. San Fran
Nov 17th
Baker logged eight tackles (three solo) during the Cardinals' 41-22 loss to the 49ers on Sunday.
#1 MLB
Cody Simon: Leads Arizona with 12 stops
Nov 17th
Simon posted 12 tackles (four solo) during the Cardinals' 41-22 loss to the 49ers on Sunday.
#3 WR
Greg Dortch: Records six catches, TD in Week 11
Nov 17th
Dortch hauled in all six targets for 66 yards and one touchdown during Sunday's 41-22 defeat to the 49ers.
#3 RB
Michael Carter: Role increases Sunday
Nov 17th
Carter had two carries for six yards and gathered in five of seven targets for 22 yards during Sunday's 41-22 loss to the 49ers.
#1 K
Chad Ryland: Converts one field goal in loss
Nov 16th
Ryland went 1-for-2 on field-goal tries and made his only PAT in Sunday's 41-22 loss to the 49ers.
#1 TE
Trey McBride: Extends TD streak to five games
Nov 16th
McBride finished with 10 receptions on 11 targets for 115 yards and a touchdown in Sunday's 41-22 loss to the 49ers.
#1 RB
Bam Knight: Scores only rushing TD for ARZ
Nov 16th
Knight (ankle) rushed five times for 24 yards and a touchdown while adding four receptions for 21 yards in Sunday's 41-22 loss to the 49ers.
#2 WR
Michael Wilson: Career performance in Week 11
Nov 16th
Wilson reeled in 15 of 18 passes for 185 yards and no touchdowns during Sunday's 41-22 defeat to the 49ers.
#1 QB
Jacoby Brissett: Sets NFL record for completions
Nov 16th
Brissett completed 47 of 57 passes for 452 yards, two touchdowns and two interceptions and rushed twice for minus-2 yards during Sunday's 41-22 loss to the 49ers.
#2 LT
Kelvin Beachum: Exits game with groin injury
Nov 16th
Beachum (groin) is questionable to return to Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
#1 SCB
Garrett Williams: Nursing shin injury
Nov 16th
Williams (shin) is questionable to return to Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
#3 SLB
BJ Ojulari: Officially active for Week 11
Nov 16th
Ojulari (knee) is active for Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
#1 RDE
Darius Robinson: Good to go vs. Niners
Nov 16th
Robinson (groin) is active for Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
#1 RG
Will Hernandez: Active in Week 11
Nov 16th
Hernandez (knee) is active for Sunday's matchup against San Francisco, Darren Urban of the Cardinals' official site reports.
#2 DT2
Walter Nolen: Good to go Week 11
Nov 16th
Nolen (knee) is active for Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
#2 MLB
Mack Wilson: Lands on injured reserve
Nov 15th
The Cardinals placed Wilson (ribs) on injured reserve Saturday, Darren Urban of the team's official site reports.
#2 LG
Hayden Conner: Won't be activated off IR
Nov 14th
Conner (knee) has been ruled out for Sunday's game against the 49ers, Zach Gershman of the Cardinals' official site reports.
#1 LG
Evan Brown: Cleared to play Week 11
Nov 14th
Brown (foot) does not have an injury designation for Sunday's game against the 49ers, Zach Gershman of the Cardinals' official site reports.
#1 RT
Jonah Williams: Won't play against San Francisco
Nov 14th
Williams (shoulder) has been ruled out for Sunday's game against the 49ers, Zach Gershman of the Cardinals' official site reports.
#2 SLB
Baron Browning: Out for Sunday vs. 49ers
Nov 14th
Browning (concussion) is officially listed as out for Sunday's game versus San Francisco, Zach Gershman of the Cardinals' official site reports.
#2 SS
Dadrion Taylor-Demerson: Won't suit up vs. 49ers
Nov 14th
Taylor-Demerson (ankle) is officially listed as out for Sunday's game versus San Francisco, Zach Gershman of the Cardinals' official site reports.
#1 LCB
Will Johnson: Won't play vs. 49ers
Nov 14th
Johnson (back) is officially listed as out for Sunday's game versus San Francisco, Zach Gershman of the Cardinals' official site reports.
#1 RCB
Max Melton: Looking good for Sunday
Nov 14th
Melton (concussion) does not carry an injury designation ahead of Sunday's game versus the 49ers, Zach Gershman of the Cardinals' official site reports.
#5 WR
Andre Baccellia: Signed to Arizona's active roster
Nov 12th
The Cardinals signed Baccellia from the practice squad to the active roster Wednesday.
#7 WR
Simi Fehoko: Placed on injured reserve
Nov 12th
Fehoko (wrist) was placed on injured reserve Wednesday, Darren Urban of the Cardinals' official site reports.
#6 WR
Zay Jones: Officially shifts to IR
Nov 12th
The Cardinals placed Jones (Achilles) on injured reserve Wednesday.
#1 WR
Marvin Harrison: Out for Week 11 due to appendicitis
Nov 12th
Cardinals coach Jonathan Gannon said Wednesday that Harrison will miss Sunday's game against the 49ers after undergoing surgery to address appendicitis, Theo Mackie of The Arizona Republic reports.
#1 LDE
Josh Sweat: Takes down QB in Week 10 loss
Nov 11th
Sweat recorded one tackle (which was a full sack), one forced fumble and one recovered fumble in Sunday's loss to Seattle.
#1 WLB
Akeem Davis-Gaither: Notches six stops in Week 10
Nov 11th
Davis-Gaither tallied six tackles (two solo) in Sunday's loss to Seattle.
#2 RCB
Denzel Burke: Picks off Darnold in Week 10 loss
Nov 10th
Burke recorded five tackles (four solo) and an interception during the Cardinals' 44-22 loss to the Seahawks on Sunday.
#2 FS
Kitan Crawford: Green light to play Week 10
Nov 9th
Crawford (ankle) is active for Sunday's game against Seattle.
#3 QB
Kyler Murray: Future in Arizona in limbo
Nov 9th
Murray, who was placed on injured reserve Wednesday due to a mid-foot sprain, is not expected to start again if he returns this season, "absent injury to Jacoby Brissett," Ian Rapoport of NFL Network reports.
#3 TE
Josiah Deguara: Back with Cards
Nov 5th
Arizona signed Deguara on Wednesday.
#4 RB
Trey Benson: Not practicing Wednesday
Nov 5th
Cardinals coach Jonathan Gannon said Wednesday that Benson (knee) is "doing well" but isn't ready to practice, Theo Mackie of The Arizona Republic reports.