Eagles at Chiefs Betting Odds, Picks and Predictions for Week 2
We have an early season rematch of Super Bowl 59. Hopefully, this contest is more competitive than that game, as the Eagles led 34-6 before the Chiefs closed the score to 40-22 to hoist the Lombardi Trophy. This year, Kansas City lost their first game of 2025 to the Los Angeles Chargers in Brazil, while the Eagles took care of business last Thursday night against the Dallas Cowboys.
Even though the season just started, the Chiefs could find themselves in an uphill battle for home-field advantage in the tough AFC if they lose this contest.
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Eagles at Chiefs Betting Odds
Eagles: Spread -1 (-105 BetMGM), -110 Moneyline (FanDuel Sportsbook)
Chiefs: Spread +1.5 (-109 BetRivers), +105 Moneyline (DraftKings Sportsbook)
Game Total: Over 46.5 points (-112 FanDuel), Under 47 (-110 Bet365 Sportsbook)
The Eagles are road favorites between 1 and 1.5 points. The moneyline for the Eagles is as low as -110, while it is +105 for the Chiefs. The posted total is between 46.5 and 47.This is one of the only times in the Patrick Mahomes era that the Chiefs are underdogs on their home field.
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Eagles at Chiefs Betting Picks
Offensively, the Chiefs came out flat in Week 1. The team lost WR Xavier Worthy (shoulder) on the third play of the game, and they were already without top WR Rashee Rice (suspension). Worthy's status for this week is unknown. Without those weapons, the rushing attack had little room to run, and Patrick Mahomes didn't get the offense rolling until the team was playing catch-up in the second half.
Defensively, the Chiefs defense had few answers for the Chargers offense. Facing the Eagles this week is a much tougher challenge. Mahomes had little success against this defense in the Super Bowl. Although the Eagles lost some talent this offseason, they still rate the edge against the Kansas City offense.
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When the Eagles have the ball, the Chiefs will likely try to go against their typical defensive trends and try to load the box to keep RB Saquon Barkley in check. Still, the dominant Philly offensive line will provide a big challenge for the Chiefs. However, the Eagles' passing attack was unable to get WRs A.J. Brown and DeVonta Smith going against the weak Dallas defense last week. They'll need to get the receivers on track this week. Philadelphia has too many ways to make an opposing defense pay for trying to stop one element. They will find a way to put points on the board.
Overall, the Eagles offense is the unit with the biggest edge on either side of the ball. It is unlikely that Kansas City will be able to slow them down. Once they fall behind, it will be difficult for the Chiefs to mount a comeback against a stingy defense coached by coordinator Vic Fangio.