Napoli are heavily favored at home against FC Zurich on Thursday, as they enter the second leg of their round of 32 tie up 3-1 on aggregate.
Chelsea are heavily favored away to Malmo on Thursday, but will fantasy players be able to rely on Eden Hazard?
Roma will book their place in the knockout rounds with a win against Qarabag on Tuesday, and they'll rely on Edin Dzeko to put them ahead.
No one has scored more Champions League goals this season than Paris Saint-Germain, and they'll look to add to their total against Celtic, who have allowed more goals than all but three teams.
Fantasy players are likely to flock to Neymar for Tuesday's eight-game Champions League slate, with PSG heavily favored against Anderlecht.
The heavy hitters are out for Wednesday's seven-game Champions League slate, with Paulo Dybala looking to break a three-match goalless drought.
Lionel Messi comes in as the most expensive player on the slate, but Alex Spalding has just the right players to pair with the Barcelona superstar without struggling with salary cap space.
There are a number of high-profile players available during Wednesday's six-game slate, but Man City's Kevin De Bruyne may be the best player at his position.
Despite failing to score in his last four games, RotoWire's Schuyler Redpath explains why Antoine Griezmann could have an explosive game Tuesday.
Edinson Cavani has put the PSG attack on his shoulders after the departure of Zlatan Ibrahimovic this summer, and Alex Spalding says the PSG striker has an ideal fantasy matchup Wednesday against FC Basel.
There are a ton of upper-tier attacking options available on Wednesday's Champions League slate, but Alex Spalding explains why Man City's Sergio Aguero is worth serious fantasy consideration.
The Champions League group stage begins Tuesday, with Manchester City's Raheem Sterling looking like a solid upside play at a much cheaper price than the elite options.
While Harry Kane and Dele Alli have been getting plenty of attention during Spurs' solid run, RotoWire's Alex Spalding reminds everyone not to forget about Christian Eriksen.
Despite failing to score in three consecutive Premier League games, a home match against Bournemouth moves Jamie Vardy to the top of the forwards rankings.
While Manchester City's defense hasn't been a tight as it was early in the season, a home match against Bournemouth puts Aleksandar Kolarov at the top of the defender rankings.