RotoWire's Juan Pablo Aravena previews La Liga's return from the COVID suspension, with Lucas Ocampos looking to make an impact against Real Betis.
Lyon will look to avenge their previous loss to Rennes, and they'll need Nabil Fekir to step up if they want to have a chance.
There will be fantasy players who try to justify fading Lionel Messi on Wednesday's two-game slate, but RotoWire's Andrew Laird explains why it's tougher to do it than on the four-game slate.
Mohamed Salah has been struggling of late, so can fantasy players turn to Sadio Mane for Wednesday's huge Champions League match against Bayern Munich?
Lionel Messi is the most expensive player on this week's Champions League slate, but RotoWire's Andrew Laird still thinks the Barcelona superstar will be the highest owned player in cash games and GPPs.
Bayern Munich have a tough matchup against Liverpool at Anfield, but that isn't likely to shy people away from Joshua Kimmich.
Tuesday's two-game slate doesn't have an abundance of firepower, but that's not enough for Adam Zdroik to think about paying up for Bayern Munich's Robert Lewandowski.
Lionel Messi is the most expensive player on this week's Champions League slate, but does RotoWire's Andrew Laird think the Barcelona superstar is worth paying up for?
Lyon need just a draw against Shahktar Donetsk on Wednesday to qualify for the round of 16, but their match should be a great one because the Ukrainian side can pass them with a win.
Tuesday's Lyon v. Manchester City match is expected to be high scoring, but it's never easy focusing on just one or two pieces from the Premier League leaders.
Bayern Munich are the biggest favorites on Wednesday's slate, and Real Madrid are also heavily favored, but RotoWire's Andrew Laird has high expectations for Manchester City's attackers.
After six goals were scored in the reverse fixture, RotoWire's Adam Zdroik is expecting plenty of fantasy scoring from Lyon and Hoffenheim on Wednesday.
Roma are strong favorites at home to CSKA Moscow on Tuesday, and Edin Dzeko's price is potentially too low to pass on.
Cristiano Ronaldo makes his long-awaited return to Old Trafford on Tuesday, but should fantasy players really consider paying up for the Juventus superstar?