Look no further for RotoWire's expert insights into today's NBA DFS slate on DraftKings. Wednesday's massive slate is riddled with breaking NBA news and a significant NBA injury report—including Domantas Sabonis, Trae Young, Zion Williamson, and Jamal Murray potentially sidelined—creating critical shifts in NBA depth charts. Our NBA DFS optimizer focuses on elite production from Nikola Jokic (averaging 84.5 DK points in his last four high-scoring games) and Cade Cunningham, whose multi-category efforts push his NBA projection into elite territory. We also highlight key value plays like Anthony Black and Aaron Holiday, who have secured 28+ minute roles. Use this fantasy basketball cheat sheet to find leverage against soft defenses.
Slate Overview
DEN at IND: Nuggets 8-2 on road; Pacers 4-7 at home
POR at CLE: Trail Blazers on three-game slide, 5-7 on road; Cavaliers 8-4 at home
SAN at ORL: Spurs 5-4 on road; Magic on three-game winning streak, 8-3 at home
LAC at ATL: Clippers on five-game slide, 2-9 on road; Hawks 4-4 at home
CHR at NY: Hornets 1-9 on road; Knicks 10-1 at home
BRO at CHI: Nets 3-7 on road; Bulls on four-game slide, 6-2 at home
DET at MIL: Pistons 8-2 on road; Bucks 6-6 at home
SAC at HOU: Kings on three-game slide; 2-9 on road; Rockets 5-2 at home
MIA at DAL: Heat 4-5 on road; Mavericks 4-9 at home
For the latest spreads and over/unders, visit RotoWire's NBA Odds page. There you can also find player props, futures, picks, articles and sportsbook bonus codes.
Injuries to Monitor
For all the latest updates, visit RotoWire's NBA Injury News page and our comprehensive NBA Injury Report.
DEN - Nikola Jokic (wrist): Probable; Jamal Murray (ankle): Questionable; Aaron Gordon (hamstring), Christian Braun (ankle): OUT
IND - Johnny Furphy (ankle): Questionable; Aaron Nesmith (knee): OUT
POR - Deni Avdija (ankle), Kris Murray (hip), Donovan Clingan (leg): Questionable; Robert Williams (knee), Jrue Holiday (calf), Matisse Thybulle (thumb), Scoot Henderson (hamstring): OUT
CLE - Lonzo Ball (illness): Probable; Sam Merrill (hand), Jarrett Allen (finger), Max Strus (foot), Larry Nance (calf): OUT
SAN - Stephon Castle (hip), Victor Wembanyama (calf): OUT
ORL - Paolo Banchero (groin): OUT
LAC - Jordan Miller (hip): Questionable; Bogdan Bogdanovic (hip), Derrick Jones (knee), Chris Paul (coach's decision): OUT
ATL - Kristaps Porzingis (illness), Trae Young (knee): OUT
CHR - LaMelo Ball (wrist): Probable; Brandon Miller (shoulder), Tre Mann (ankle), Pat Connaughton (calf): OUT
NY - Mitchell Robinson (rest), OG Anunoby (hamstring), Landry Shamet (shoulder): OUT
BRO - Terance Mann (ribs), Cam Thomas (hamstring): OUT
CHI - Patrick Williams (wrist), Julian Phillips (illness), Lachlan Olbrich (calf): Probable; Tre Jones (ankle), Jalen Smith (hamstring), Dalen Terry (calf), Zach Collins (wrist): Questionable; Isaac Okoro (back): Doubtful; Coby White (calf), Kevin Huerter (hamstring), Noa Essengue (shoulder): OUT
DET - Duncan Robinson (ankle): Questionable; Marcus Sasser (hip): OUT
MIL - Giannis Antetokounmpo (adductor): Probable; Gary Harris (Achilles), Bobby Portis (eye), Kevin Porter (back): Questionable
SAC - Malik Monk (shoulder): Probable; Dennis Schroder (hip): Questionable; Domantas Sabonis (knee): OUT
HOU - Steven Adams (rest): Questionable; Dorian Finney-Smith (ankle), Tari Eason (oblique): OUT
MIA - Pelle Larsson (foot): Questionable; Norman Powell (ankle): OUT
DAL - P.J. Washington (ankle), Daniel Gafford (ankle): Questionable; Dereck Lively (foot): OUT
Elite Players
Guards
Josh Giddey, Bulls 
($9,800) vs. Nets
The Nets have one of the worst defenses in the league, which Giddey will look to exploit Wednesday. The 23-year-old point guard has yet to log fewer than 37.3 DK points this season and is one of just a handful of Bulls players not listed on the injury report. He should have another prime opportunity to stuff the stat sheet against Brooklyn and has averaged 20.6 points, 10.0 rebounds, 7.8 assists and 1.4 steals per game in his last five outings.
Donovan Mitchell, Cavaliers 
($9,500) vs. Trail Blazers
Mitchell is fresh off a 43-point performance during Monday's win over Indiana and is preparing for another favorable matchup against the Trail Blazers, who rank in the bottom third of the league in defensive rating and are entering the second half of a back-to-back set. The star guard has generated at least 43.8 DK points in five of his last six contests, averaging 31.5 points, 6.2 rebounds, 6.0 assists and 1.2 steals in 34.8 minutes per game during that span.
Forwards/Centers
Nikola Jokic, Nuggets 
($13,400) at Pacers
As to be expected, Jokic sits atop the board with a lucrative $13,400 salary. While the price is high, it's for a good reason, as the three-time MVP has yet to log fewer than 51.3 DK points this season. He's coming off his fourth game with at least 84.5 DK points on the campaign during Monday's loss to Dallas, and he has averaged 27.4 points, 12.2 rebounds, 11.2 assists and 1.4 combined steals-plus-blocks across 35.0 minutes per contest in his last five appearances.
Giannis Antetokounmpo, Bucks 
($11,400) vs. Pistons
Despite the outside noise and trade rumors, Antetokounmpo continues to deliver on a nightly basis. The two-time MVP has been a mainstay on the injury report of late, though he's likely to suit up in his fourth consecutive contest following a four-game absence due to a left adductor strain. Over his last three games, the superstar has averaged 28.3 points, 10.0 rebounds, 4.7 assists and 1.3 steals in 26.3 minutes per contest. He has yet to record fewer than 38.0 DK points when he plays at least 19 minutes.
Alperen Sengun, Rockets 
($9,700) vs. Kings
Sengun and the Rockets are gearing up to face a lackluster Kings defense, and Sacramento remains without star center Domantas Sabonis (knee). Sengun is coming off his best fantasy performance of the season in Monday's loss to Utah and will aim to take advantage of a favorable matchup Wednesday. Over his last four outings, the star big man has averaged 23.0 points, 7.5 assists, 5.8 rebounds, 1.5 blocks and 1.0 steals in 34.0 minutes per contest.
Expected Chalk
Cade Cunningham, Pistons 
($10,600) at Bucks
Cunningham scored 18 points and shot 0-for-4 from three-point range during Monday's win over the Hawks, though he still finished with 55.0 DK points thanks to his best defensive performance of the season. The star guard hasn't recorded fewer than 46.8 DK points since Oct. 27 and will look to stay hot against a struggling Milwaukee squad. Over his last five appearances, Cunningham has averaged 30.4 points, 8.8 rebounds, 7.6 assists, 1.8 steals and 1.0 blocks across 37.6 minutes per contest.
Mid-Range Money
Cooper Flagg, Mavericks 
($7,100) vs. Heat
Flagg has been impressive of late, notching 42.5-plus DK points in three straight outings. The rookie has struggled from three-point range in his last six games, though he has still finished with more than 26 DK points in all of them, during which he has averaged 20.8 points, 7.3 rebounds, 4.0 assists and 1.7 steals in 34.3 minutes per contest.
Kon Knueppel, Hornets 
($6,700) at Knicks
Knueppel and the Hornets face a Knicks squad that is on the second leg of a back-to-back set, marking their third game in four days. While the rookie struggled in a loss to New York on Nov. 26, the Hornets will be without Brandon Miller (shoulder) and Tre Mann (ankle) this time around, leaving plenty of opportunity for Knueppel. The 20-year-old forward has registered at least 26.8 DK points in seven of his last eight appearances, averaging 20.3 points, 5.4 rebounds, 3.3 assists and 0.9 steals per game during that stretch.
Value Picks
Anthony Black, Magic 
($5,500) vs. Spurs
Black continues to impress in fantasy and real life, scoring in double figures in eight straight games. The 21-year-old has logged at least 28 minutes in each of those eight outings, averaging 18.1 points, 3.6 rebounds, 3.6 assists and 1.9 steals in 31.1 minutes per contest. He hasn't finished with fewer than 26.3 DK points since Nov. 14.
Toumani Camara, Trail Blazers 
($5,300) at Cavaliers
Although the Trail Blazers are preparing for their second game in as many days, Camara should still see all the minutes he can handle with the club rolling out another busy injury report. The 25-year-old forward has tallied at least 20.3 DK points in seven consecutive contests, averaging 14.4 points, 6.3 rebounds, 2.3 assists and 1.9 combined steals-plus-blocks across 33.4 minutes per game during that span.
Aaron Holiday, Rockets ($4,100) vs. Kings
Holiday has logged at least 20 minutes off the bench in four consecutive contests, including 33 minutes in Monday's loss to Utah. The 29-year-old has slowly emerged as the backup point guard to Amen Thompson after barely playing in the beginning of the season, and Holiday should continue to see meaningful playing time against Sacramento. He has posted at least 17.0 DK points in four straight outings, during which he has averaged 14.3 points, 2.3 assists, 1.8 rebounds and 1.0 steals across 27.3 minutes per contest.
