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Chiefs vs Colts Odds, Lines, Spreads & Totals 2025

Colts
23.5 Pts
Chiefs
27.0 Pts
Sunday November 23, 2025 at 1:00 PM ET
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IND
Colts Injury Report
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KC
Chiefs Injury Report
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IND
Colts Lineup
Inactives
    None reported yet.
KC
Chiefs Lineup
Inactives
    None reported yet.
IND
Colts News
#2 DT2
DeForest Buckner: Gets treatment for neck injury
Nov 14th
Buckner received regenerative stem cell treatment to address the neck injury that landed him on injured reserve Nov. 7, James Boyd of The Athletic reports.
#1 LCB
Sauce Gardner: Productive in debut
Nov 11th
Gardner recorded six tackles (four solo) and a pass defended during Indianapolis' win over the Falcons on Sunday.
#1 FS
Camryn Bynum: Records sack in win
Nov 11th
Bynum tallied five tackles (four solo) during the Colts' win versus the Falcons on Sunday.
#1 WLB
Germaine Pratt: Totals seven stops Sunday
Nov 11th
Pratt logged seven tackles (three solo) and recovered a fumble in Indianapolis' win over the Falcons on Sunday.
#3 RB
Ameer Abdullah: One grab in win
Nov 11th
Abdullah caught his lone target for eight yards in Sunday's 31-25 win over the Falcons.
#2 RB
Tyler Goodson: Handles one carry in Week 10
Nov 11th
Goodson rushed once for four yards in Sunday's 31-25 win over the Falcons.
#1 SS
Nick Cross: Sacks Penix in Week 10 overtime win
Nov 10th
Cross registered seven tackles (three solo), including 1.0 sacks, during the Colts' 31-25 overtime win over the Falcons on Sunday.
#1 MLB
Zaire Franklin: Team-high 10 tackles in OT win
Nov 10th
Franklin tallied 10 tackles (six solo), including 1.0 sacks, during the Colts' 31-25 overtime win over the Falcons on Sunday.
#3 WR
Josh Downs: Falls back to earth in Week 10
Nov 10th
Downs secured one of two targets for three yards during the Colts' 31-25 overtime win over the Falcons on Sunday.
#1 K
Michael Badgley: Misses two kicks Week 10
Nov 9th
Badgley went 2-for-3 on field-goal attempts and 1-for-2 on extra-point tries during the Colts' 31-25 overtime win over the Falcons on Sunday.
#1 WR
Michael Pittman: Limited to two catches Sunday
Nov 9th
Pittman brought in both targets for 19 yards in the Colts' 31-25 overtime win over the Falcons in Berlin on Sunday.
#2 WR
Alec Pierce: Gets into end zone in win
Nov 9th
Pierce brought in four of seven targets for 84 yards and a touchdown in the Colts' 31-25 overtime victory against the Falcons in Berlin on Sunday.
#1 QB
Daniel Jones: Mixed bag in overseas win
Nov 9th
Jones completed 19 of 26 passes for 255 yards with a touchdown and an interception while adding seven carries for 53 yards in the Colts' 31-25 overtime win over the Falcons in Berlin on Sunday. He also committed three fumbles, losing one.
#1 TE
Tyler Warren: Busy day in Berlin win
Nov 9th
Warren brought in eight of 10 targets for 99 yards in the Colts' 31-25 overtime win against the Falcons in Berlin on Sunday.
#1 RB
Jonathan Taylor: Bounces back via MVP-caliber effort
Nov 9th
Taylor rushed 32 times for 244 yards and three touchdowns while bringing in all three targets for 42 yards in the Colts' 31-25 overtime win against the Falcons on Sunday in Berlin.
#1 LDT
Grover Stewart: Returns to Sunday's game
Nov 9th
Stewart (head) was cleared to return to Sunday's game against the Falcons, Mike Chappell of Fox 59 News Indianapolis reports.
#4 TE
Will Mallory: Inactive again for Week 10
Nov 9th
Mallory (coach's decision) is inactive for Sunday's game against the Falcons in Berlin.
#4 RB
DJ Giddens: Inactive for second straight
Nov 9th
Giddens (coach's decision) is inactive for Sunday's game against the Falcons in Berlin.
#5 WR
Anthony Gould: Downgraded to out for Week 10
Nov 8th
Gould (knee) has been downgraded to out for Sunday's game against the Falcons.
#6 WR
Laquon Treadwell: Signed to active roster
Nov 8th
The Colts signed Treadwell to the active roster from their practice squad Saturday, Amanda Foster of the team's official site reports.
#2 LDE
Tyquan Lewis: Out for Week 10
Nov 7th
Lewis (groin) has been ruled out ahead of Sunday's matchup against the Falcons.
#2 RDE
Samson Ebukam: Missing more time
Nov 7th
Ebukam (knee) has been ruled out ahead of Sunday's matchup against the Falcons.
#3 RCB
Charvarius Ward: Working with trainer
Nov 5th
Ward (concussion) was spotted doing work on the field with a trainer Wednesday, Joel A. Erickson of The Indianapolis Star reports.
KC
Chiefs News
#1 SS
Chamarri Conner: Leads team in stops in defeat
Nov 17th
Conner tallied eight tackles (five solo), including 1.0 sacks, in a Week 11 loss to Denver on Sunday.
#1 K
Harrison Butker: Makes pair of FGs in defeat
Nov 16th
Butker converted both of his field-goal attempts and one of two extra-point tries in Sunday's 22-19 loss to the Broncos.
#3 WR
Hollywood Brown: Four grabs in Sunday's loss
Nov 16th
Brown caught all four of his targets for 40 yards in Sunday's 22-19 loss to the Broncos.
#1 TE
Travis Kelce: Sets franchise record in loss
Nov 16th
Kelce caught nine of 13 targets for 91 yards and a touchdown in Sunday's 22-19 loss to the Broncos.
#1 WR
Rashee Rice: Limited yards on six catches Sunday
Nov 16th
Rice caught six of nine targets for 38 yards in Sunday's 22-19 loss to the Broncos.
#2 RB
Kareem Hunt: Extends TD streak in loss
Nov 16th
Hunt carried the ball 13 times for 59 yards and a touchdown and caught one of two targets for three yards in Sunday's 22-19 loss to the Broncos.
#1 QB
Patrick Mahomes: Comes up short in Denver
Nov 16th
Mahomes completed 29 of 45 passes for 276 yards and a touchdown with an interception in Sunday's 22-19 loss to the Broncos. He added three rushing yards on one carry.
#1 LG
Kingsley Suamataia: Won't return Sunday
Nov 16th
Suamataia (concussion) has been ruled out for the rest of Sunday's game against the Broncos.
#2 LT
Jaylon Moore: Good to go against Denver
Nov 16th
Moore (illness) is active for Sunday's game against the Broncos, Matt McMullen of the Chiefs' official site reports.
#2 RG
Jaylon Moore: Good to go against Denver
Nov 16th
Moore (illness) is active for Sunday's game against the Broncos, Matt McMullen of the Chiefs' official site reports.
#2 RT
Jaylon Moore: Good to go against Denver
Nov 16th
Moore (illness) is active for Sunday's game against the Broncos, Matt McMullen of the Chiefs' official site reports.
#4 RB
Elijah Mitchell: Active versus Denver
Nov 16th
Mitchell is active for Sunday's game against the Broncos, Matt McMullen of the Chiefs' official site reports.
#1 LDE
George Karlaftis: Past thumb injury
Nov 14th
Karlaftis (thumb) has no injury designation ahead of Sunday's matchup against the Broncos.
#1 RB
Isiah Pacheco: Ruled out by Chiefs
Nov 14th
Pacheco (knee) has been ruled out for Sunday's game against the Broncos.
#2 WR
Xavier Worthy: Good to go against Broncos
Nov 14th
Worthy (ankle) doesn't have an injury designation for Sunday's game against the Broncos.
#1 LT
Josh Simmons: Practicing to begin week
Nov 12th
Simmons (personal) was a full participant at practice Wednesday.
#1 MLB
Nick Bolton: Racks up 14 tackles
Nov 4th
Bolton recorded 14 tackles (five solo), including one tackle for loss in Sunday's 28-21 loss to the Bills.
#1 LCB
Trent McDuffie: Huge performance against Buffalo
Nov 4th
McDuffie recorded 12 tackles (five solo), including one sack and one tackle for loss in Sunday's 28-21 loss to the Bills.