This article is part of our NFL Picks series.
NFL Week 2 Spreads and Key Line Movement
The goal of this article is to look at the key line moves for the week and what they mean in terms of betting. Key numbers in the NFL to watch for are 3, 7, 6, 14, and 10. When a line crosses through one of these, it is a significant move that warrants attention.
Now that Week One is in the books (except for MNF), we have injuries and the classic overreactions in Week Two to consider. This is when line moves really become a factor in handicapping which way to bet. While we had 10 home dogs in Week 1, we only have one this week.
The trend I see in Week Two is a TON of low totals due to matchups with poor offenses and/or strong defenses. We have five favorites of 9 points or higher whereas in Week 1, the highest favorites ended up at -7.
Sign up at Caesars Sportsbook using our Caesars Sportsbook promo code for your $1,250 First Bet on Caesars plus tier and reward credits.
NFL Week 2 Odds
Los Angeles Chargers @ Kansas City Chiefs (-3.5) O/U 54.5
New York Jets @ Cleveland Browns (-6.5) O/U 42.5
Washington Commanders @ Detroit Lions (-2.0) O/U 47.0
Miami Dolphins @ Baltimore Ravens (-4) O/U 45.5
Indianapolis Colts (-4.5) @ Jacksonville Jaguars O/U 45.5
Carolina Panthers @ New York Giants (-2.5) O/U 42.5
New England Patriots @ Pittsburgh Steelers (-1.0) O/U 41.5
Atlanta Falcons @ Los Angeles Rams (-11.5) O/U 48.0
Seattle Seahawks @ San Francisco 49ers (-9.5) O/U 42.5
Houston Texans @ Denver Broncos (-10.5) O/U 43.5
Arizona Cardinals @ Las Vegas Raiders (-3.5) O/U 52.0
Chicago Bears @ Green Bay Packers (-9.5) O/U 44.0
Tennessee Titans @ Buffalo Bills (-9.5) O/U 50.0
Minnesota Vikings @ Philadelphia Eagles (-3.0) O/U 49.5
NFL Week 2 Line Movement: Cincinnati Bengals 
at Dallas Cowboys 
This line opened Cowboys -2 but has immediately been taken off the board due to the thumb injury to Dak Prescott. There are some oddsmakers that have already reopened this line with the Bengals at -7. That is a 9-point swing, which is much higher than what we would normally see on a quarterback change. I wrote about this in last week's article and typically seven points in the highest adjustment that oddsmakers will take on the top quarterbacks.
The original total of 50.5 will most likely be reopened around 42-43 points with about a 7-to-9-point adjustment down as well.
New users can take advantage of the Fanduel promo code that nets $150 on a $5 bet, win or lose.
NFL Week 2 Line Movement: New York Jets 
at Cleveland Browns 
We saw significant line movement in the Panthers/Browns and Ravens/Jets last week. This week, we see it all on the Browns who have moved from -4.5 in May to -6.5 and back down to -6.0 in most spots. The total has dropped from 43 to 42 and I think it will continue to move down as neither team will be able to move the ball in the air. This should be a very run-heavy game with both teams starting backup quarterbacks.
Sign up at the DraftKings Sportsbook using RotoWire's DraftKings Promo Code to get $200 in free bets.
NFL Week 2 Line Movement: Atlanta Falcons 
at Los Angeles Rams 
This game opened Rams -13.5 all the way back in May and ticked down to -12 after the Thursday night loss. It is now sitting at Rams -11.5 (dipped to -11) after the Falcons' close loss at home to the Saints. If the Falcons had won, I think it could have gone all the way to -10 and I still think we could see that happen.
The Rams' offensive line looked awful and the Falcons recorded four sacks against the Saints. Matthew Stafford struggled as he did not have much time to set up in the pocket and he also looked rusty, perhaps from the lingering elbow issue.
The total has come down from 49.5 and is sitting at the key number of 48.
Use the BetMGM Bonus Code for a risk-free bet up to $1,000.
NFL Week 2 Line Movement: Tennessee Titans 
at Buffalo Bills 
This game is the perfect case example for line movement 101 as you have the Bills who blew out the Rams in prime time on Thursday and the Titans who lost at home against the Giants.
The line opened Bills -7.0 and moved to -8.5 right after the Thursday night win and now it stands at -9.5 after the Titans' loss. I would expect this line to hit -10 rather quickly and stay there.
The total opened 47 and then jumped to 51 and back down to 50. This is also a double revenge spot for the Bills who lost at Tennessee each of the last two years.
If you're looking to wager on the NFL this season, RotoWire has a full suite of betting pages and tools with everything you need from the latest NFL odds to weekly NFL picks along with a wide variety of NFL futures and NFL player futures. Be sure to use our page to see what's available across the country and in your state, along with the latest promo codes and sign-up bonuses. Make use of the best sports betting sites and NFL betting sites to get the most out of your NFL betting experience.
If you are looking for picks, check out our NFL Week 2 picks, predictions, and best bets.
