Philadelphia Eagles vs San Francisco 49ers Odds, Week 19, 2025

#1 SS

Ji'Ayir Brown: Moves to strong safety in 2025

Jan 8th

Brown had 76 tackles (44 solo), two interceptions and one forced fumble in 17 regular-season starts with the 49ers in 2025.

#1 SCB

Upton Stout: Takes over as slot CB in first year

Jan 8th

Stout finished with 82 tackles (43 solo), one sack and one forced fumble across 16 regular-season games in 2025.

#6 WR

Jordan Watkins: Little involvement in rookie year

Jan 8th

Watkins was active for four games in 2025 and finished the regular season with two receptions on three targets for 26 yards.

#5 WR

Skyy Moore: Finds home in SF as return man

Jan 8th

Moore finished the 2025 regular season with five receptions for 87 yards, two carries for 11 yards and 1,198 combined return yards in 17 appearances.

#1 LT

Trent Williams: Upgrades to limited practice

Jan 8th

Williams (hamstring) was a limited participant in Thursday's practice, Cam Inman of The San Jose Mercury News reports.

#1 TE

George Kittle: Limited again Thursday

Jan 8th

Kittle (ankle) was a limited practice participant Thursday, Cam Inman of The San Jose Mercury News reports.

#2 MLB

Fred Warner: Seen running Thursday, still on IR

Jan 8th

Warner (ankle) was seen sprinting on the side during Thursday's practice, Matt Barrows of The Athletic reports.

#2 WR

Ricky Pearsall: Not practicing Thursday

Jan 8th

Pearsall (knee/ankle) isn't participating in Thursday's practice, Matt Barrows of The Athletic reports.

#3 RB

Jordan James: Gets some late run on ST

Jan 7th

James did not record a touch while appearing in three games for the 49ers in 2025.

#3 TE

Luke Farrell: Finds end zone in fifth year

Jan 7th

Farrell finished his first regular season with San Francisco grabbing 11 of 14 targets for 85 yards and two touchdowns across 17 games.

#4 RB

Isaac Guerendo: Falls out of favor in 2025

Jan 7th

Guerendo was only utilized on special teams this season, finishing with 100 kick return yards across 14 active games.

#2 QB

Mac Jones: Thrives as Purdy's backup in 2025

Jan 7th

Jones finished the regular season completing 70 percent of his pass attempts for 2,151 yards, 13 touchdowns and six interceptions across 11 games.

#3 LDE

Keion White: Not practicing Wednesday

Jan 7th

White (hamstring) won't participate in practice Wednesday, Matt Barrows of The Athletic reports.

#1 WLB

Dee Winters: Not practicing Wednesday

Jan 7th

Winters (ankle) did not practice in Wednesday's session, Matt Barrows of The Athletic reports.

#8 WR

Jacob Cowing: Returning from IR

Jan 7th

The 49ers designated Cowing (hamstring) to return from injured reserve Wednesday.

#3 MLB

Tatum Bethune: Moved to IR

Jan 7th

The 49ers placed Bethune (groin) on injured reserve Wednesday.

#1 MLB

Eric Kendricks: Signs to active roster

Jan 7th

The 49ers signed Kendricks from the practice squad to the active roster Wednesday.

#1 SLB

Luke Gifford: Questionable for wild-card round

Jan 5th

San Francisco head coach Kyle Shanahan said Monday that Gifford (quadriceps) will be evaluated throughout the week to determine his status for the wild-card round, Nick Wagoner of ESPN.com reports.

#1 QB

Brock Purdy: Not expected to miss practice time

Jan 5th

San Francisco head coach Kyle Shanahan said Monday that he expects Purdy (shoulder) to be a full participant in practice throughout the week leading up to Sunday's wild-card game at Philadelphia, David Lombardi of SFStandard.com reports.

#1 K

Eddy Pineiro: Provides only offense for SF

Jan 4th

Pineiro converted his only field-goal attempt of 48 yards in Saturday's 13-3 loss to Seattle.

#2 TE

Jake Tonges: Stuck on ST with Kittle back

Jan 4th

Tonges logged 11 snaps on special teams and was not used on offense in Saturday's 13-3 loss to the Seahawks.

#4 WR

Kendrick Bourne: Non-factor in Saturday's loss

Jan 4th

Bourne failed to catch his only target in Saturday's 13-3 loss to the Seahawks.

#2 RB

Brian Robinson: Just two carries in loss to SEA

Jan 4th

Robinson rushed two times for nine yards and was not targeted as a receiver in Saturday's 13-3 loss to Seattle.

#3 WR

Demarcus Robinson: Draws start in Week 18

Jan 4th

Robinson had three receptions on four targets for 24 yards in Saturday's 13-3 loss to the Seahawks.

#1 WR

Jauan Jennings: Disappointing Week 18 performance

Jan 3rd

Jennings recorded four receptions on six targets for 35 yards in Saturday's 13-3 loss to the Seahawks.

#1 RB

Christian McCaffrey: Stifled by Seattle

Jan 3rd

McCaffrey rushed the ball eight times for 23 yards in Saturday's 13-3 loss to the Seahawks. He added six receptions on seven targets for 34 yards.

#2 WLB

Curtis Robinson: Healthy scratch again

Jan 3rd

Robinson (coach's decision) is inactive for Saturday night's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.

#2 LDE

Yetur Gross-Matos: Good to go for Week 18

Jan 1st

Gross-Matos (knee) will not carry an injury designation into Saturday's contest against the Seahawks.

#1 FB

Kyle Juszczyk: Good to go for Saturday

Jan 1st

Juszczyk (hip) does not have an injury designation for Saturday's matchup versus Seattle.

#1 LCB

Renardo Green: No limitations Tuesday

Dec 30th

Green (neck) is expected to be listed as a full participant at practice Tuesday, Nick Wagoner of ESPN.com reports.

#1 FS

Malik Mustapha: Tallies three tackles vs. Chicago

Dec 29th

Mustapha registered three tackles (two solo) and one pass defense during San Francisco's 42-38 win over Chicago on Sunday.

#3 QB

Kurtis Rourke: Officially out for 2025

Dec 29th

Rourke (knee) will remain on the 49ers' reserve/non-football injury list for the rest of the 2025 season, Matt Maiocco of NBC Sports Bay Area reports.