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Cardinals vs Jaguars Odds, Lines, Spreads & Totals 2025

Jaguars
Cardinals
Sunday November 23, 2025 at 4:05 PM ET
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JAX
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JAX
Jaguars Lineup
Inactives
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Cardinals Lineup
Inactives
JAX
Jaguars News
#2 RB
Bhayshul Tuten: Limited to 17 yards Sunday
Nov 23rd
Tuten rushed seven times for 17 yards while failing to catch his only target in Sunday's 27-24 win over the Cardinals.
#2 WR
Jakobi Meyers: Scores first TD of season with JAX
Nov 23rd
Meyers hauled in four of six targets for 50 yards and a touchdown in Sunday's 27-24 overtime win against Arizona.
#3 WR
Parker Washington: Team-high seven targets in win
Nov 23rd
Washington secured five of seven targets for 71 yards and one touchdown in Jacksonville's overtime win over Arizona on Sunday.
#1 QB
Trevor Lawrence: Mixed bag in OT win Sunday
Nov 23rd
Lawrence completed 18 of 30 pass attempts for 256 yards, three touchdowns and three interceptions while rushing five times for 29 yards and a lost fumble in Sunday's 27-24 overtime win against Arizona.
#1 RB
Travis Etienne: Productive as RB1 in OT win
Nov 23rd
Etienne (shoulder) took 15 carries for 86 yards while catching three of four targets for 30 yards and a touchdown in Sunday's 27-24 overtime win against Arizona.
#1 K
Cam Little: Hits two long field goals in OT win
Nov 23rd
Little made both of his field-goal attempts and all three of his extra-point tries during the Jaguars' 27-24 overtime win over the Cardinals on Sunday.
#1 TE
Brenton Strange: Leading receiver in OT win
Nov 23rd
Strange (hip) finished with five receptions on as many targets for 93 yards in Sunday's 27-24 overtime win against Arizona.
#1 LCB
Jarrian Jones: Active Sunday
Nov 23rd
Jones (quadriceps) is active for Sunday's game against the Cardinals, Demetrius Harvey of The Florida Times-Union reports.
#1 SCB
Jourdan Lewis: Remaining out Week 12
Nov 23rd
Lewis (neck) is inactive for Sunday's clash against the Cardinals.
#1 WR
Brian Thomas: Good chance for Week 13 return
Nov 23rd
Thomas (ankle), who won't play Sunday against the Cardinals, has a good chance to return to action in Week 13 versus the Titans, Tom Pelissero of NFL Network reports.
#2 ROLB
Yasir Abdullah: Won't play against Arizona
Nov 21st
Abdullah (finger) has been ruled out for Sunday's game against the Cardinals, Michael DiRocco of ESPN.com reports.
#1 RT
Anton Harrison: Ruled out for Week 12
Nov 21st
Harrison (knee) has been ruled out for Sunday's game against the Cardinals, Michael DiRocco of ESPN.com reports.
#1 RCB
Greg Newsome: Good to go Week 12
Nov 21st
Newsome (ankle) does not carry an injury designation into Sunday's game against the Cardinals.
#1 RDE
Travon Walker: Out for Week 12
Nov 21st
Walker (knee) has been ruled out for Sunday's game against the Cardinals, Michael DiRocco of ESPN.com reports.
#2 TE
Hunter Long: Won't play Sunday
Nov 21st
Long (hip/knee) has been ruled out for Sunday's game at Arizona, Michael DiRocco of ESPN.com reports.
#1 FS
Andrew Wingard: Five tackles in easy victory
Nov 18th
Wingard recorded five tackles (three solo) with one pass defensed in Sunday's 35-6 win over the Chargers.
#1 SS
Antonio Johnson: Continues to fill in for Murray
Nov 18th
Johnson recorded two tackles (one solo), one pass defensed and one interception in Sunday's 35-6 win over the Chargers.
#5 WR
Dyami Brown: Non-factor against Chargers
Nov 18th
Brown failed to secure his only target in Sunday's 35-6 win over the Chargers.
#1 LOLB
Foyesade Oluokun: Logs five stops vs. Bolts
Nov 17th
Oluokun recorded five total tackles (three solo) and two passes defensed in Sunday's 35-6 win over the Chargers.
#3 TE
Johnny Mundt: Notches two receptions
Nov 17th
Mundt caught two of three targets for 25 yards during Sunday's 35-6 win against the Chargers.
#4 TE
Quintin Morris: Catches first pass of 2025
Nov 17th
Morris secured one of three targets for 11 yards during Sunday's 35-6 win against the Chargers.
#3 RB
LeQuint Allen: Garners eight garbage-time carries
Nov 17th
Allen rushed eight times for 36 yards and returned two kickoffs for 55 yards during Sunday's 35-6 win against the Chargers.
#4 WR
Tim Patrick: Hauls in one-yard TD pass
Nov 16th
Patrick finished Sunday's 35-6 win over the Chargers with three catches (on four targets) for 20 yards and a touchdown.
#4 RB
Cody Schrader: Healthy scratch
Nov 16th
Scrader (coach's decision) is inactive for Sunday's game against the Chargers.
#2 LCB
Travis Hunter: Set to remain two-way player in '26
Nov 16th
The Jaguars plan to continue utilizing Hunter (knee) as their top wide receiver and as a matchup cornerback in 2026, Ian Rapoport of NFL Network reports.
#1 LG
Ezra Cleveland: Set to return Week 11
Nov 14th
Cleveland (knee) does not have an injury designation for Sunday's game against the Chargers.
#1 ROLB
Dennis Gardeck: Good to go Sunday
Nov 14th
Gardeck (chest) has no injury designation ahead of Sunday's matchup against the Chargers.
#1 MLB
Devin Lloyd: Racks up eight stops in Week 10
Nov 11th
Lloyd finished Sunday's loss to the Texans with eight tackles (two solo).
#6 WR
Austin Trammell: Secures first catches of 2025
Nov 10th
Trammell caught two of three targets for 33 yards during Sunday's 36-29 loss to the Texans.
ARI
Cardinals News
#3 RB
Michael Carter: Leading rusher on five carries
Nov 23rd
Carter rushed five times for 28 yards while adding three receptions for 30 yards in Sunday's 27-24 overtime loss to the Jaguars.
#3 WR
Greg Dortch: Nets another TD in Week 12
Nov 23rd
Dortch recorded six catches (on nine targets) for 53 yards and one touchdown, took two carries for minus-5 yards and returned five kickoffs for 127 yards during Sunday's 27-24 loss to the Jaguars.
#1 RB
Bam Knight: Cashes in early TD
Nov 23rd
Knight rushed 10 times for 12 yards and a touchdown while catching four of five targets for 20 yards in Sunday's 27-24 overtime loss to the Jaguars.
#1 QB
Jacoby Brissett: Throws for over 300 yards Sunday
Nov 23rd
Brissett completed 33 of 49 pass attempts for 317 yards and a touchdown while taking three carries for 20 yards in Sunday's 27-24 loss to Jacksonville in overtime.
#2 WR
Michael Wilson: Continues to thrive as No. 1 WR
Nov 23rd
Wilson hauled in 10 of 15 targets for 118 yards in Sunday's 27-24 overtime loss to Jacksonville.
#1 TE
Trey McBride: Nine catches in OT loss
Nov 23rd
McBride corralled nine of 10 targets for 79 yards in Sunday's 27-24 overtime loss to the Jaguars.
#1 K
Chad Ryland: Misses FGA in loss to Jacksonville
Nov 23rd
Ryland made one of two field-goal attempts and all three of his extra points in Arizona's 27-24 overtime loss to the Jaguars on Sunday.
#1 RG
Will Hernandez: Questionable with hip
Nov 23rd
Hernandez (hip) is questionable to return to Sunday's game against the Jaguars, Josh Weinfuss of ESPN.com reports.
#1 DT2
Walter Nolen: Ruled out with knee
Nov 23rd
Nolen (knee) has been ruled out and will not return to Sunday's game against the Jaguars, Josh Weinfuss of ESPN.com reports.
#2 LT
Kelvin Beachum: Cleared to play Week 12
Nov 23rd
Beachum (groin) is active for Sunday's game against the Jaguars, Darren Urban of the Cardinals' official site reports.
#2 RT
Kelvin Beachum: Cleared to play Week 12
Nov 23rd
Beachum (groin) is active for Sunday's game against the Jaguars, Darren Urban of the Cardinals' official site reports.
#1 RDE
Darius Robinson: Cleared to play Week 12
Nov 23rd
Robinson (groin) is active for Sunday's game against the Jaguars, Darren Urban of the Cardinals' official site reports.
#1 LCB
Will Johnson: Won't play Week 12
Nov 23rd
Johnson (back) is inactive for Sunday's game against the Jaguars, Darren Urban of the Cardinals' official site reports.
#1 SCB
Garrett Williams: Good to go vs. Jacksonville
Nov 23rd
Williams (ankle) is active for Sunday's game against the Jaguars, Darren Urban of the Cardinals' official site reports.
#3 SS
Darren Hall: Back on Cardinals' active roster
Nov 22nd
The Cardinals signed Hall from the practice squad to the active roster Saturday.
#4 TE
Pharaoh Brown: Elevated to active roster
Nov 22nd
The Cardinals elevated Brown from the practice squad to the active roster Saturday.
#2 SS
Dadrion Taylor-Demerson: Ruled out
Nov 21st
Taylor-Demerson (ankle) has been ruled out for Sunday's game against the Jaguars, Bo Brack of GoPHNX.com reports.
#5 RT
Jonah Williams: Heads to IR with shoulder injury
Nov 21st
The Cardinals placed Williams (shoulder) on injured reserve Friday.
#5 RB
Trey Benson: Won't return this week
Nov 21st
Benson (knee) has been ruled out for Sunday's game against Jacksonville, Bo Brack of GoPHNX.com reports.
#4 RB
Jermar Jefferson: Signed to active roster
Nov 21st
The Cardinals signed Jefferson to their active roster Friday, Darren Urban of the Cardinals' official site reports.
#2 SLB
Baron Browning: Ruled out for Week 12
Nov 21st
Browning (concussion) won't play Sunday against the Jaguars, Bo Brack of PHNX Sports reports.
#2 RB
Emari Demercado: Officially out for Week 12
Nov 19th
Cardinals coach Jonathan Gannon said Wednesday that Demercado (ankle) has been ruled out for Sunday's game against the Jaguars, Theo Mackie of The Arizona Republic reports.
#1 WR
Marvin Harrison: Ruled out for Week 12
Nov 19th
Cardinals head coach Jonathan Gannon said Wednesday that Harrison (appendix) is ruled out for Sunday's contest against the Jaguars, Theo Mackie of The Arizona Republic reports.
#2 RCB
Denzel Burke: Limited impact in loss
Nov 18th
Burke recorded two tackles (one solo) with one pass defensed in Sunday's 41-22 loss to the 49ers.
#1 WLB
Akeem Davis-Gaither: Makes four tackles
Nov 18th
Davis-Gaither recorded four tackles (one solo) in Sunday's 41-22 loss to the 49ers.
#4 WR
Xavier Weaver: Minimal production against 49ers
Nov 18th
Weaver caught two of three targets for 15 yards in Sunday's 41-22 loss to the 49ers.
#2 TE
Elijah Higgins: Two grabs in loss
Nov 18th
Higgins caught two of three targets for 11 yards in Sunday's 41-22 loss to the 49ers.
#1 FS
Budda Baker: Posts eight stops vs. San Fran
Nov 17th
Baker logged eight tackles (three solo) during the Cardinals' 41-22 loss to the 49ers on Sunday.
#1 MLB
Cody Simon: Leads Arizona with 12 stops
Nov 17th
Simon posted 12 tackles (four solo) during the Cardinals' 41-22 loss to the 49ers on Sunday.
#3 SLB
BJ Ojulari: Officially active for Week 11
Nov 16th
Ojulari (knee) is active for Sunday's game against the 49ers, Darren Urban of the Cardinals' official site reports.
#2 MLB
Mack Wilson: Lands on injured reserve
Nov 15th
The Cardinals placed Wilson (ribs) on injured reserve Saturday, Darren Urban of the team's official site reports.
#2 LG
Hayden Conner: Won't be activated off IR
Nov 14th
Conner (knee) has been ruled out for Sunday's game against the 49ers, Zach Gershman of the Cardinals' official site reports.
#1 LG
Evan Brown: Cleared to play Week 11
Nov 14th
Brown (foot) does not have an injury designation for Sunday's game against the 49ers, Zach Gershman of the Cardinals' official site reports.
#1 RCB
Max Melton: Looking good for Sunday
Nov 14th
Melton (concussion) does not carry an injury designation ahead of Sunday's game versus the 49ers, Zach Gershman of the Cardinals' official site reports.
#5 WR
Andre Baccellia: Signed to Arizona's active roster
Nov 12th
The Cardinals signed Baccellia from the practice squad to the active roster Wednesday.
#7 WR
Simi Fehoko: Placed on injured reserve
Nov 12th
Fehoko (wrist) was placed on injured reserve Wednesday, Darren Urban of the Cardinals' official site reports.
#6 WR
Zay Jones: Officially shifts to IR
Nov 12th
The Cardinals placed Jones (Achilles) on injured reserve Wednesday.
#1 LDE
Josh Sweat: Takes down QB in Week 10 loss
Nov 11th
Sweat recorded one tackle (which was a full sack), one forced fumble and one recovered fumble in Sunday's loss to Seattle.
#2 FS
Kitan Crawford: Green light to play Week 10
Nov 9th
Crawford (ankle) is active for Sunday's game against Seattle.
#3 QB
Kyler Murray: Future in Arizona in limbo
Nov 9th
Murray, who was placed on injured reserve Wednesday due to a mid-foot sprain, is not expected to start again if he returns this season, "absent injury to Jacoby Brissett," Ian Rapoport of NFL Network reports.