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Bills vs Buccaneers Odds, Lines, Spreads & Totals 2025

Buccaneers
20.8 Pts
Bills
26.8 Pts
Sunday November 16, 2025 at 1:00 PM ET
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Buccaneers Injury Report
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Bills Injury Report
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Buccaneers Lineup
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Bills Lineup
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Buccaneers News
#2 ROLB
Anthony Nelson: Doesn't practice Thursday
Nov 13th
Nelson (illness) did not practice Thursday.
#1 SS
Antoine Winfield: Limited again Thursday
Nov 13th
Winfield (foot) was a limited participant in Thursday's practice.
#1 ROLB
Haason Reddick: Another DNP on Thursday
Nov 13th
Reddick (ankle/knee) did not practice Thursday.
#7 WR
Jalen McMillan: Season debut not imminent
Nov 13th
Buccaneers head coach Todd Bowles said Nov. 5 that McMillan's timeline for a return from injured reserve hasn't changed after it was recently revealed that the receiver is recovering from multiple broken bones in his neck in addition to a severe sprain, Greg Auman of Fox Sports reports.
#2 WR
Chris Godwin: Logs another limited practice
Nov 13th
Godwin (fibula) was limited in practice Thursday.
#1 RB
Bucky Irving: Limited again Thursday
Nov 13th
Irving (shoulder) was a limited participant in Thursday's practice.
#1 LG
Ben Bredeson: Ominous start to practice week
Nov 12th
Bredeson (hamstring) was estimated as a non-participant in Wednesday's practice walkthrough.
#1 NT
Vita Vea: Working through back issue
Nov 12th
Vea (back) was a limited participant in Wednesday's walkthrough practice.
#1 LCB
Jamel Dean: Tallies four tackles in Week 10
Nov 11th
Dean posted four tackles (all solo) in Sunday's loss to New England.
#1 LILB
SirVocea Dennis: Posts quiet stat line in Week 10
Nov 11th
Dennis notched one tackle and one defensed pass in Sunday's loss to the Patriots.
#4 RB
Josh Williams: Dealt six-game ban
Nov 11th
Williams received a six-game suspension Tuesday for violating the NFL's performance-enhancing substances policy, Greg Auman of Fox Sports reports.
#1 RILB
Lavonte David: Paces team in tackles again
Nov 11th
David supplied nine tackles (six solo) in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#2 TE
Payne Durham: Sees first target since Week 2
Nov 11th
Durham failed to catch his only target, his first since Week 2, in Sunday's 28-23 loss to the Patriots.
#6 WR
Kameron Johnson: Contributes 71 all-purpose yards
Nov 11th
Johnson rushed once for 11 yards, failed to bring in his only target, returned two kickoffs for 48 yards and ran back two punts for 12 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#4 WR
Sterling Shepard: Three catches in Week 10 loss
Nov 11th
Shepard brought in three of four targets for 20 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 FS
Tykee Smith: Picks off Maye in Week 10 loss
Nov 10th
Smith registered eight tackles (four solo) and an interception during the Buccaneers' 28-23 loss to the Patriots on Sunday.
#3 WR
Tez Johnson: Two TD grabs in Week 10 loss
Nov 9th
Johnson brought in four of five targets for 42 yards and two touchdowns in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#3 RB
Sean Tucker: Outgains White in Week 10 loss
Nov 9th
Tucker rushed nine times for 53 yards and brought in one of two targets for minus-2 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 TE
Cade Otton: Stellar numbers in loss
Nov 9th
Otton secured nine of 12 targets for 82 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#2 RB
Rachaad White: Eclipses 50 total yards in loss
Nov 9th
White rushed 10 times for 38 yards and brought in all five targets for 16 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 QB
Baker Mayfield: Three-TD effort wasted in loss
Nov 9th
Mayfield completed 28 of 43 passes for 273 yards with three touchdowns and no interceptions in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 K
Chase McLaughlin: Makes three kicks Week 10
Nov 9th
McLaughlin connected on his lone field-goal attempt and made both of his point-after tries during the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 WR
Emeka Egbuka: Paces pass catchers in loss
Nov 9th
Egbuka brought in six of 13 targets for 115 yards and a touchdown in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 RG
Luke Haggard: Not suiting up Week 10
Nov 9th
Haggard (shoulder) is inactive for Sunday's game against the Patriots, Scott Smith of the Buccaneers' official site reports.
#1 RT
Luke Goedeke: Cleared to return Week 10
Nov 9th
Goedeke (foot) is active for Sunday's game against the Patriots, Scott Smith of the Buccaneers' official site reports.
#3 ROLB
Markees Watts: Out for Sunday
Nov 7th
Watts (knee) has been ruled out ahead of Sunday's matchup against the Patriots, Greg Auman of Fox Sports reports.
#1 SCB
Jacob Parrish: Full session Wednesday
Nov 5th
Parrish (oblique) practiced in full Wednesday.
BUF
Bills News
#2 WLB
Shaq Thompson: Practices in full
Nov 13th
Thompson (hamstring) returned to full practice participation Thursday.
#1 SCB
Taron Johnson: Returns to full participation
Nov 13th
Johnson (groin) returned to full practice participation Thursday.
#1 MLB
Terrel Bernard: Returns to full participation
Nov 13th
Bernard (ankle) returned to full practice participation Thursday.
#1 WR
Khalil Shakir: Limited by ankle and ribs Thursday
Nov 13th
Shakir (ankle/ribs) was a limited participant in Thursday's practice.
#1 TE
Dalton Kincaid: Not seen at practice Thursday
Nov 13th
Kincaid (hamstring) wasn't spotted at practice Thursday, Alaina Getzenberg of ESPN.com reports.
#1 RCB
Christian Benford: Limited Wednesday
Nov 12th
Benford (groin) was limited in Wednesday's practice.
#2 LDE
A.J. Epenesa: Practices in fill
Nov 12th
Epenesa (concussion) logged a full practice Wednesday, Alaina Getzenberg of ESPN.com reports.
#3 TE
Jackson Hawes: Hits paydirt in loss to Miami
Nov 12th
Hawes secured one of two targets for 26 yards and a touchdown during Buffalo's loss to the Dolphins in Week 10.
#4 WR
Elijah Moore: Makes two catches in loss to Miami
Nov 12th
Moore secured both of his targets for nine yards during Buffalo's loss to the Dolphins in Week 10.
#6 WR
Curtis Samuel: Secures only target in Week 10 loss
Nov 12th
Samuel secured his only target for 21 yards during Buffalo's loss to the Dolphins in Week 10.
#3 WR
Joshua Palmer: Set to practice fully Wednesday
Nov 12th
Palmer (knee/ankle) is in line to practice fully Wednesday, Alaina Getzenberg of ESPN.com reports.
#1 SS
Jordan Poyer: Leading tackler in loss
Nov 11th
Poyer recorded eight tackles (three solo) in Buffalo's loss to Miami on Sunday.
#1 RDE
Joey Bosa: Logs four stops Sunday
Nov 11th
Bosa logged four solo tackles during Buffalo's loss to Miami on Sunday.
#3 DT2
T.J. Sanders: Has practice window opened
Nov 11th
Buffalo designated Sanders to return from IR on Tuesday, Alaina Getzenberg of ESPN.com reports.
#3 LDE
Landon Jackson: Placed on IR
Nov 11th
The Bills placed Jackson (knee) on injured reserve Tuesday.
#1 FS
Cole Bishop: Logs second interception of 2025
Nov 10th
Bishop totaled seven tackles (six solo) and an interception during the Bills' 30-13 loss to the Dolphins on Sunday.
#2 TE
Dawson Knox: Three catches in Week 10 loss
Nov 9th
Knox secured three of four targets for 37 yards in the Bills' 30-13 loss to the Dolphins on Sunday.
#2 WR
Keon Coleman: Gets into end zone Sunday
Nov 9th
Coleman secured three of eight targets for 46 yards and a touchdown in the Bills' 30-13 loss to the Dolphins on Sunday.
#1 K
Matt Prater: Quiet day in Week 10 loss
Nov 9th
Prater made his lone extra-point attempt during the Bills' 30-13 loss to the Dolphins on Sunday.
#1 RB
James Cook: Opportunities capped in loss
Nov 9th
Cook rushed 13 times for 53 yards and brought in all five targets for 24 yards in the Bills' 30-13 loss to the Dolphins on Sunday. He also lost a fumble.
#1 QB
Josh Allen: Chased by Dolphins in loss
Nov 9th
Allen completed 28 of 40 passes for 306 yards with two touchdowns and one interception and added four rushes for 31 yards in the Bills' 30-13 loss to the Dolphins on Sunday. He also lost a fumble.
#1 DT2
DaQuan Jones: Cleared to play Miami
Nov 9th
Jones (calf) is active for Sunday's game against the Dolphins.
#3 LCB
Dorian Strong: No timeline on return
Nov 3rd
Head coach Sean McDermott was unable to provide a timeline on Strong's (neck) return Monday, Matt Parrino of The Syracuse Post-Standard reports.
#3 RDE
Michael Hoecht: Out for year with torn Achilles
Nov 3rd
The Bills placed Hoecht on injured reserve Monday due to a torn right Achilles which will sideline him for the rest of the 2025, season, Alaina Getzenberg of ESPN.com reports.
#5 WR
Tyrell Shavers: Just one catch vs. Kansas City
Nov 3rd
Shavers caught his only target for seven yards in Sunday's 28-21 win over the Chiefs.
#2 RB
Ty Johnson: Finds end zone in Week 9
Nov 3rd
Johnson rushed twice for eight yards and a touchdown during Sunday's 28-21 win over the Chiefs. He also caught both of his targets for 12 yards.
#3 RB
Ray Davis: Handles kick-return duties Sunday
Nov 3rd
Davis played three of the Bills' 64 offensive snaps and tallied 105 kick-return yards in Sunday's 28-21 win over the Chiefs.
#4 LDT
Ed Oliver: Could return by playoffs
Nov 2nd
Oliver (biceps) has a chance to return for the first week of the playoffs, Ian Rapoport of NFL Network reports.
#3 SS
Taylor Rapp: Expected to miss remainder of 2025
Oct 31st
Rapp underwent surgery on his injured knee this week and is likely going to miss the remainder of the season, Alaina Getzenberg of ESPN.com reports.