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Bills vs Buccaneers Odds, Lines, Spreads & Totals 2025

Buccaneers
22.0 Pts
Bills
27.5 Pts
Sunday November 16, 2025 at 1:00 PM ET
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Buccaneers Injury Report
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Bills Injury Report
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Buccaneers Lineup
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Buccaneers News
#1 FS
Tykee Smith: Picks off Maye in Week 10 loss
Nov 10th
Smith registered eight tackles (four solo) and an interception during the Buccaneers' 28-23 loss to the Patriots on Sunday.
#2 WR
Chris Godwin: Expected to miss Week 11
Nov 10th
Coach Todd Bowles said Monday that he doesn't expect Godwin (fibula) to play next Sunday against the Bills, Rick Stroud of the Tampa Bay Times reports.
#1 RB
Bucky Irving: Not expected to play Week 11
Nov 10th
Coach Todd Bowles said Monday that he doesn't expect Irving (shoulder/foot) to play Week 11 against the Bills, Rick Stroud of the Tampa Bay Times reports.
#3 WR
Tez Johnson: Two TD grabs in Week 10 loss
Nov 9th
Johnson brought in four of five targets for 42 yards and two touchdowns in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#3 RB
Sean Tucker: Outgains White in Week 10 loss
Nov 9th
Tucker rushed nine times for 53 yards and brought in one of two targets for minus-2 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 TE
Cade Otton: Stellar numbers in loss
Nov 9th
Otton secured nine of 12 targets for 82 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#2 RB
Rachaad White: Eclipses 50 total yards in loss
Nov 9th
White rushed 10 times for 38 yards and brought in all five targets for 16 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 QB
Baker Mayfield: Three-TD effort wasted in loss
Nov 9th
Mayfield completed 28 of 43 passes for 273 yards with three touchdowns and no interceptions in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 K
Chase McLaughlin: Makes three kicks Week 10
Nov 9th
McLaughlin connected on his lone field-goal attempt and made both of his point-after tries during the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 WR
Emeka Egbuka: Paces pass catchers in loss
Nov 9th
Egbuka brought in six of 13 targets for 115 yards and a touchdown in the Buccaneers' 28-23 loss to the Patriots on Sunday.
#1 LG
Ben Bredeson: Won't return vs. New England
Nov 9th
Bredeson (hamstring) has been ruled out for the rest of Sunday's game against the Patriots.
#1 RG
Luke Haggard: Not suiting up Week 10
Nov 9th
Haggard (shoulder) is inactive for Sunday's game against the Patriots, Scott Smith of the Buccaneers' official site reports.
#1 RT
Luke Goedeke: Cleared to return Week 10
Nov 9th
Goedeke (foot) is active for Sunday's game against the Patriots, Scott Smith of the Buccaneers' official site reports.
#3 ROLB
Markees Watts: Out for Sunday
Nov 7th
Watts (knee) has been ruled out ahead of Sunday's matchup against the Patriots, Greg Auman of Fox Sports reports.
#1 ROLB
Haason Reddick: Ruled out for Sunday
Nov 7th
Reddick (ankle/knee) has been ruled out ahead of Sunday's matchup against the Patriots, Greg Auman of Fox Sports reports.
#1 SCB
Jacob Parrish: Full session Wednesday
Nov 5th
Parrish (oblique) practiced in full Wednesday.
#2 TE
Payne Durham: No catches through eight games
Oct 29th
Durham went without a target while playing 32 of the Buccaneers' 58 snaps on offense in Sunday's 23-3 win over the Saints.
#4 WR
Sterling Shepard: Minimal output in Week 8 win
Oct 29th
Shepard finished with an eight-yard reception on two targets in Sunday's 23-3 win over the Saints.
#4 RB
Josh Williams: Career-high four carries in win
Oct 28th
Williams rushed four times for 11 yards in the Buccaneers' 23-3 win over the Saints on Sunday.
#1 LOLB
Yaya Diaby: Quiet in Week 8 win
Oct 28th
Diaby recorded one assisted tackle during Sunday's win over the Saints.
#1 LCB
Jamel Dean: Records six stops vs. Saints
Oct 28th
Dean made six tackles (five solo) and had one forced fumble during Sunday's win over New Orleans.
BUF
Bills News
#1 FS
Cole Bishop: Logs second interception of 2025
Nov 10th
Bishop totaled seven tackles (six solo) and an interception during the Bills' 30-13 loss to the Dolphins on Sunday.
#1 TE
Dalton Kincaid: Considered week-to-week
Nov 10th
Kincaid is week-to-week after suffering a hamstring injury during Sunday's loss to the Dolphins, NFL reporter Jordan Schultz reports.
#2 TE
Dawson Knox: Three catches in Week 10 loss
Nov 9th
Knox secured three of four targets for 37 yards in the Bills' 30-13 loss to the Dolphins on Sunday.
#2 WR
Keon Coleman: Gets into end zone Sunday
Nov 9th
Coleman secured three of eight targets for 46 yards and a touchdown in the Bills' 30-13 loss to the Dolphins on Sunday.
#1 WR
Khalil Shakir: Seven catches in Week 10 loss
Nov 9th
Shakir secured seven of nine targets for 58 yards in the Bills' 30-13 loss to the Dolphins on Sunday.
#1 K
Matt Prater: Quiet day in Week 10 loss
Nov 9th
Prater made his lone extra-point attempt during the Bills' 30-13 loss to the Dolphins on Sunday.
#1 RB
James Cook: Opportunities capped in loss
Nov 9th
Cook rushed 13 times for 53 yards and brought in all five targets for 24 yards in the Bills' 30-13 loss to the Dolphins on Sunday. He also lost a fumble.
#1 QB
Josh Allen: Chased by Dolphins in loss
Nov 9th
Allen completed 28 of 40 passes for 306 yards with two touchdowns and one interception and added four rushes for 31 yards in the Bills' 30-13 loss to the Dolphins on Sunday. He also lost a fumble.
#3 LDE
Landon Jackson: Ruled out against Miami
Nov 9th
Jackson (knee) has been ruled out for the remainder of Sunday's contest against the Dolphins.
#1 SCB
Taron Johnson: Not playing Sunday
Nov 9th
Johnson (groin) is inactive for Sunday's matchup with the Dolphins.
#1 RCB
Christian Benford: Inactive Sunday
Nov 9th
Benford (groin) is inactive for Sunday's game against the Dolphins.
#1 DT2
DaQuan Jones: Cleared to play Miami
Nov 9th
Jones (calf) is active for Sunday's game against the Dolphins.
#3 WR
Joshua Palmer: Inactive versus Miami
Nov 9th
Palmer (knee/ankle) is inactive for Sunday's game against the Dolphins.
#1 RDE
Joey Bosa: Good to go
Nov 7th
Bosa (wrist) does not carry an injury designation for Sunday's game against the Dolphins.
#1 MLB
Terrel Bernard: Cleared for Week 10
Nov 7th
Bernard (ankle) doesn't carry an injury designation for Sunday's game against the Dolphins.
#2 WLB
Shaq Thompson: Ruled out for Week 10
Nov 7th
Thompson (hamstring) won't play Sunday against the Dolphins, head coach Sean McDermott revealed Friday, Maddy Glab of the Bills' official site reports.
#2 LDE
A.J. Epenesa: Ruled out for Week 10
Nov 7th
Epenesa (concussion) won't play Sunday against the Dolphins, head coach Sean McDermott revealed Friday, Maddy Glab of the Bills' official site reports.
#3 LCB
Dorian Strong: No timeline on return
Nov 3rd
Head coach Sean McDermott was unable to provide a timeline on Strong's (neck) return Monday, Matt Parrino of The Syracuse Post-Standard reports.
#3 RDE
Michael Hoecht: Out for year with torn Achilles
Nov 3rd
The Bills placed Hoecht on injured reserve Monday due to a torn right Achilles which will sideline him for the rest of the 2025, season, Alaina Getzenberg of ESPN.com reports.
#5 WR
Tyrell Shavers: Just one catch vs. Kansas City
Nov 3rd
Shavers caught his only target for seven yards in Sunday's 28-21 win over the Chiefs.
#4 WR
Elijah Moore: Minimal output in win
Nov 3rd
Moore caught his lone target for 28 yards during Sunday's 28-21 win over the Chiefs.
#2 RB
Ty Johnson: Finds end zone in Week 9
Nov 3rd
Johnson rushed twice for eight yards and a touchdown during Sunday's 28-21 win over the Chiefs. He also caught both of his targets for 12 yards.
#3 RB
Ray Davis: Handles kick-return duties Sunday
Nov 3rd
Davis played three of the Bills' 64 offensive snaps and tallied 105 kick-return yards in Sunday's 28-21 win over the Chiefs.
#4 LDT
Ed Oliver: Could return by playoffs
Nov 2nd
Oliver (biceps) has a chance to return for the first week of the playoffs, Ian Rapoport of NFL Network reports.
#3 SS
Taylor Rapp: Expected to miss remainder of 2025
Oct 31st
Rapp underwent surgery on his injured knee this week and is likely going to miss the remainder of the season, Alaina Getzenberg of ESPN.com reports.
#1 WLB
Matt Milano: Practices in full
Oct 29th
Milano (pectoral) will practice in full Wednesday, Maddy Glab of the Bills' official site reports.
#1 SS
Jordan Poyer: Signed to active roster
Oct 28th
The Bills signed Poyer off the practice squad Tuesday.