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Pearsall hauled in six of seven targets for 96 yards in Sunday's 37-24 win over Tennessee.
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Jennings finished with three receptions on five targets for 37 yards and two touchdowns in Sunday's 37-24 win over the Titans.
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Kittle brought in eight of nine targets for 88 yards and a touchdown in Sunday's 37-24 win over the Titans.
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Purdy completed 23 of 30 pass attempts for 295 yards and three touchdowns while adding seven carries for 44 yards and a lost fumble in Sunday's 37-24 win over the Titans.
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Pineiro went 3-for-3 on field-goal attempts and made all four of his PATs in Sunday's 37-24 win over the Titans.
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McCaffrey (back) took 22 carries for 73 yards and a touchdown while grabbing his only target for 14 yards in Sunday's 37-24 win over Tennessee.
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James (coach's decision) is inactive for Sunday's matchup against Tennessee.
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McCaffrey (back) is active for Sunday's game against the Titans.
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Elliot (knee) has been ruled out for Sunday's game against the Titans, Matt Maiocco of NBC Sports Bay Area reports.
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The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.
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Although he was added to the 49ers' injury report Saturday, McCaffrey (back) is expected to play against the Titans on Sunday, Adam Schefter of ESPN reports.
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McCaffrey has been added to the 49ers' injury report due to a back injury, and he is listed as questionable for Sunday's game against the Titans, Matt Barrows of The Athletic reports.
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Rourke (knee) is out for Sunday's game versus the Titans, Cam Inman of The San Jose Mercury News reports.
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Martin (concussion) is out for Sunday's game versus Tennessee, Cam Inman of The San Jose Mercury News reports.
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Gross-Matos (hamstring) is out for Sunday's game versus Tennessee, Cam Inman of The San Jose Mercury News reports.
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Bethune (ankle) has been ruled out for Sunday's game against the Titans, Cam Inman of The San Jose Mercury News reports.
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Okuayinonu (ankle) has been ruled out for Sunday's game against the Titans, Cam Inman of The San Jose Mercury News reports.
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Juszczyk (ribs) does not have an injury designation for Sunday's game against the Titans, Cam Inman of The San Jose Mercury News reports.
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McCaffrey (illness) doesn't have an injury designation for Sunday's game against the Titans, Cam Inman of The San Jose Mercury News reports.
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McCaffrey (illness) is practicing Friday, Noah Furtado of the San Francisco Chronicle reports.
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Bethune (ankle) did not practice Thursday.
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Juszczyk (ribs) logged a limited practice Thursday.
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McCaffrey was limited at Thursday's practice due to an illness, David Lombardi of SFStandard.com reports.
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San Francisco designated Gross-Matos (knee) to return from IR on Thursday, Matt Maiocco of NBC Sports Bay Area reports.
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Rourke (knee) practiced in full Wednesday.
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