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The Latest Bills Odds For NFL Season 2025

Buffalo Bills
1-0 (0-0 in the AFC East)
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BUF
Bills Week 2 Matchup
Sunday at 1:00 pm EST
Buffalo Bills
26.5 Pts
@
New York Jets
20.0 Pts
Moneyline
DraftKings DraftKings
BUF -310
Spread
DraftKings DraftKings
BUF -6.5
Over Under
DraftKings DraftKings
46.5 Pts
PROBABILITY with vig removed
BUF Bills Win (-310)
72.6%
NYJ Jets Win (+250)
27.4%
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Projected Record: 14-3 (6-0 AFC East)
BUF
Bills Injury Report
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BUF
Bills News
DE
Greg Rousseau: Dealing with knee injury
Sep 10th
Rousseau was a limited participant in Wednesday's practice due to a knee injury.
LB
Shaq Thompson: Sits out again Wednesday
Sep 10th
Thompson (hamstring) did not practice Wednesday.
CB
Taron Johnson: Misses practice with quad injury
Sep 10th
Johnson (quadriceps) did not practice Wednesday.
CB
Tre'Davious White: Limited Wednesday
Sep 10th
White (groin) was limited in practice Wednesday.
RB
James Cook: Logs limited practice
Sep 10th
Cook (hamstring) was listed as limited in Wednesday's practice.
TE
Dawson Knox: Limited in practice Wednesday
Sep 10th
Knox (hip) was limited in Wednesday's practice.
RB
Ty Johnson: Handles two carries in opener
Sep 10th
Johnson rushed twice for 24 yards and failed to secure either of his two targets in Sunday's 41-40 win over the Ravens.
WR
Elijah Moore: Minimal production against Ravens
Sep 10th
Moore caught his lone target for three yards in Sunday's 41-40 win over the Ravens.
WR
Joshua Palmer: Records five catches in win
Sep 10th
Palmer caught five of nine targets for 61 yards in Sunday's 41-40 win over the Ravens.
TE
Dawson Knox: Two catches against Ravens
Sep 10th
Knox caught both of his targets for 20 yards in Sunday's 41-40 win over the Ravens.
BUF
Bills Depth Chart
Quarterback  QB
Running Back  RB
Wide Receiver  WR
Tight End  TE
Fullback  FB