NFL Week 13 Predictions, Picks, Props and Best Bets for Every Game

Thanks everyone for following along throughout the NFL season. I cut the "Best Bets" section a bit short to make sure everything was submitted on time before the festivities kick off Thursday. I'm expecting plenty of good football over the first two days and then....well let's just say I'm hoping the food coma I'll be in will carry over to some of the Sunday contests so I can get a quality nap in.

Week 12 Record ATS: 4-9-1
Week 12 Record on Totals: 8-6

2025 Season Record ATS: 75-86-2
2025 Season Record on Totals: 92-72

NFL Week 13 Picks For Each Game

NFL Week 13 Predictions

In this article, we also take a look at NFL Week 13 odds and our predictions for each NFL game. Home teams are listed last.

Packers vs. Lions

I think it's just easier to assume the Lions will win this one. Green Bay is incredibly banged whether it be Josh Jacobs (knee), Jordan Love (shoulder) or the myriad of defensive injuries it has. Detroit hasn't played perfect this season, but I just think they're a well-coached team and have an identity in terms of aggressiveness. That should win in hostile conditions like Ford Field.

Spread Pick: Lions -2.5
Total Pick: Over 48.5

Chiefs vs. Cowboys

I guess I shouldn't be surprised the Chiefs are favored to this degree, but I just don't know what I'm supposed to think about this game. The Cowboys always play the Thanksgiving home game with a certain level of confidence and I'm not comfortable assuming the Chiefs can just keep pitching a seven-inning shutout for the next two months straight. I'd assume Kansas City will win, but this feels like a difficult spread to cover.

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Spread Pick: Cowboys +3.5
Total Pick: Under 52.5

Bengals vs. Ravens

I just don't think Baltimore is playing at a level where they should be a touchdown favorite over anyone, much less a returning Joe Burrow (foot). Cincinnati's defense has gotten marginally better in past weeks, but it doesn't matter if Lamar Jackson continues to play to the level he has since returning from that hamstring injury. I'm slightly worried this game will just be overall ugly, as most AFC North games tend to be.

Spread Pick: Bengals +7
Total Pick: Under 51.5

Bears vs. Eagles

It's completely fine to question Chicago's legitimacy as an 8-4 team. Their schedule has been very favorable and they've won games that felt like the opponent just gave away. At the same time, I have more faith in what Chicago can do, and more importantly, the identity that they have, than whatever is going on in Philadelphia right now. Much like the Ravens, the Eagles should not be a touchdown favorite over anyone especially a team that has figured out to win games despite things not always going perfectly.

Spread Pick: Bears +7
Total Pick: Under 44.5

Rams vs. Panthers

I think this is going to be another long day at the office for Bryce Young. I guess it's possible that Carolina could get a bit more of the running game going and therefore keeping the game close, but that feels like an unlikely outcome even for the home team.

Spread Pick: Rams -10
Total Pick: Under 44.5

49ers vs. Browns

I'm glad that Shedeur Sanders is getting another start. I think it seemed fairly obvious Las Vegas was a rudderless ship that the rookie could pick up a win over, but it's a lot different against a defense that's well coached and motivated. I am legitimately worried that Myles Garrett could single handily keep this game competitive for Cleveland, but I have to trust that Kyle Shanahan will have a gameplan specifically made to stop his record-breaking pace.

Spread Pick: 49ers -4.5
Total Pick: Under 36.5

Texans vs. Colts

If C.J. Stroud (concussion) is available, I'd take the Texans to cover. At least as of this writing it sounds like he could miss another week, and I do think Davis Mills will end up biting them in that case with Indianapolis' offense far more potent than anything Houston has faced in recent weeks. And yes, that includes whatever the Bills are doing right now. I assume these two teams will split their divisional matchups this year, but I'll lean towards the home team to start.

Spread Pick: Colts -4.5
Total Pick: Over 44.5

Saints vs. Dolphins

This strikes me as a relatively high number. Arguably I don't think the Dolphins should be favored by this much over anyone, nor do I think the Saints are truly that bad of a team in context with Miami. I do feel entirely comfortable with the over being in play regardless.

Spread Pick: Saints +5.5
Total Pick: Over 42.5

Falcons vs. Jets

Part of the issue with having so many good games for the holiday stretch means the rest of Sunday is just littered with awful games with this one possibly topping the list. Please don't bet this game in any capacity. The result won't make any sense and no one is going to care about the result 24 hours later.

Spread Pick: Falcons -2.5
Total Pick: Under 39.5

Cardinals vs. Buccaneers

Evidently Baker Mayfield is trying to play in this one. It seems ridiculous to me that he'll be out there after we last saw him rolling in agony throwing a ball 20 yards short of the end zone on a hail mary, but I won't deny that guy's toughness. If Mayfield plays this isn't even a discussion. However, if Tampa walks into any game with Teddy Bridgewater as the starting quarterback, they will lose, no questions asked. This line to me suggest Mayfield doesn't play, but I'm trusting my gut he'll be out there.

Spread Pick: Buccaneers -3
Total Pick: Over 43.5

Jaguars vs. Titans

I still have belief in Cam Ward and Tennessee to look like a better team than what they've been all season. I just don't think it'll happen this week. Trevor Lawrence is completely capable of goofing away any game, but I'd just be surprised if the Titans are hanging around enough to make it a one-score game when it happens.

Spread Pick: Jaguars -6.5
Total Pick: Over 41.5

Vikings vs. Seahawks

I don't care if J.J. McCarthy plays or not. Minnesota's offense can't function with the quarterbacks currently available on their roster. Seattle is going to make this game over by halftime.

Spread Pick: Seahawks -11.5
Total Pick: Over 41.5

Raiders vs. Chargers

This is an extraordinarily high line for a team that has arguably one of the worst offensive lines in the entire NFL. I'll put it this way; I wouldn't be surprised if the Raiders miraculously look more competent as an offense post Chip Kelly and ride the efforts of Maxx Crosby to a surprise cover, if not win come Sunday. But do I want to bet on that outcome? Do I assume it will happen? I'm not sure how anyone can watch Vegas' disinterested and inefficient roster and suggest something like that can legitimately happen. It'd just be projecting a narrative that has no quantitative substance.

Spread Pick: Chargers -9.5
Total Pick: Over 40.5

Bills vs. Steelers

This is another annoying line because Buffalo has not played well enough to be favored to this extent over a playoff-caliber team. I understand the Steelers really aren't a playoff caliber team either, but it feels like a pick-your-poison between two disappointing teams. I trust Buffalo to figure this out at some point, and they might have to with a few other AFC wildcard hopefuls sniffing around a potential higher seed.

Spread Pick: Bills -3.5
Total Pick: Over 46.5

Broncos vs. Commanders 

I legitimately have no idea why this line is the way it is. I guess Jayden Daniels (elbow) could return? Maybe Terry McLaurin (quadriceps) will also be active? I suppose those things could help Washington's defense, but how are they supposed to stop Denver's offense? And why is the total only at 43.5? Whenever I'm horrendously off on this sort of line I feel like I'm walking straight into an ambush, but march on I will.

Spread Pick: Broncos -5.5
Total Pick: Over 43.5

Giants vs. Patriots

The Jameis Winston experience was cute, but I expect Jaxson Dart (concussion) to return and usher out any chance of a competent team once more. It's not that the rookie can't win football games or play well, but the offense is undeniably more efficient and effective with Winston as the quarterback. That's the byproduct of letting a young quarterback get through his lumps as a pro and having an offense so reliant on his mobility as well.

Spread Pick: Patriots -7.5
Total Pick: Over 46.5

NFL Week 13 Best Bets

In the interest of making sure this gets published before the holidays, I'm just jotting down the few specific lines that I like overall. Happy Thanksgiving to everyone and may your turkey be moist and all your parlays hit.

• Broncos -5.5
• Over 43.5 WAS/DEN
• Over 42.5 NO/MIA
• Patriots, Broncos, 49ers moneylines