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Best Bets for Indianapolis Colts vs. Kansas City Chiefs | Kansas City Chiefs -3.0 (-120)
The Kansas City Chiefs will look to bounce back from a loss to Denver when they host the Indianapolis Colts on Sunday afternoon. Oddsmakers have the Chiefs -3.0 at home with a 50.5 point total.
New customers can claim bet365 Bonus Code ROTOWIRE to get $150 in bonus bets instantly. Win or lose, a $5 first bet placed on any sport, including any of our three best bets on the Colts and Chiefs, returns $150 in bonus bets right away.
Colts' running back Jonathan Taylor has led Indianapolis to an 8-2 record, rushing for over 1,100 yards and 15 touchdowns this season. He'll face a Chiefs run defense allowing a pedestrian 4.2 YPC and 10 rushing touchdowns through 10 games.
Indianapolis is coming out of a bye week and are a popular side from public bettors this week. We saw what happened to the Colts when Pittsburgh shut down their rushing attack, so expect a similar blue print from Chiefs DC Steve Spagnuolo.
Kansas City needs a win to keep itself in the playoff mix, currently third in the AFC West at 5-5. Patrick Mahomes will respond accordingly, especially against a Colts defense that has surrendered 24 or more points in four of its last five games.
Let's lay -3.0 with Kansas City as a field goal favorite at home in what feels like a must-win game.
Best Bets for Indianapolis Colts vs. Kansas City Chiefs | Patrick Mahomes O 268.5 Passing Yards (-110)
Kansas City's run game is not very effective right now. This means we're going to see Patrick Mahomes throw quite a few passes against a Colts secondary that has allowed three quarterbacks to go over 300 passing yards.
Mahomes' current passing yards prop is set to 268.5. This is a high total but he's gone over this line in three of his past four starts for the Chiefs.
Let's back the three-time Super Bowl MVP to continue peppering a healthier wide receiving corps with plenty of targets. Bet on Mahomes to go over 268.5 passing yards for the sixth time in 2025 against Indianapolis.
Best Bets for Indianapolis Colts vs. Kansas City Chiefs
Let's turn our attention to the Indianapolis Colts. Specifically, rookie tight end, Tyler Warren.
The Colts' 14th overall pick has been very reliable for Daniel Jones, hauling in 50 receptions for 617 yards and three touchdowns in 10 games. He's had seven to 10 targets in back-to-back games for Indianapolis.
Warren's receiving yards total is set to 49.5. He's gone over this number in four of his past five games, including six of ten starts.
Assuming the game script goes in favor of Kansas City covering -3.0, the Colts will be forced to throw the football at a higher rate. Let's bet on Warren to go over 49.5 receiving yards at -110 odds.
Best Bets for Indianapolis Colts vs. Kansas City Chiefs Picks
- Kansas City Chiefs -3.0 (-120)
- Patrick Mahomes O 268.5 Passing Yards (-110)
- Tyler Warren O 49.5 Receiving Yards (-110)
Best Events to Use the bet365 Bonus Code For November 23
- NFL: Minnesota Vikings vs. Green Bay Packers. Packers -6.0 with a 41.5 point total in this NFC North rivalry from Lambeau Field. 1 p.m. ET kickoff on FOX.
- NFL: Philadelphia Eagles vs. Dallas Cowboys. Eagles -3.5 with a 47.5 point total on the road against their biggest division rival. 4:25 p.m. ET kickoff on FOX.
- NHL: Minnesota Wild vs. Winnipeg Jets. The Jets will look to improve to 7-3 at home when they host the red-hot Wild. Puck drop at 4 p.m. ET on ESPN+.
- NBA: Orlando Magic vs. Boston Celtics. Jaylen Brown and the Celtics host Franz Wagner's Magic at TD Garden. Tip-off at 6 p.m. ET.
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