Rams vs Panthers Predictions & Odds for NFL Playoffs Wild Card Round (2026)

The Los Angeles Rams take on the Carolina Panthers in what looks like the biggest mismatch of the Wild Card Round. The latest Rams vs Panthers odds list LA as a whopping 10.5-point favorite, which you can bet using a bet365 bonus code. 

Below, the RotoWire staff will give you our expert Rams vs Panthers predictions, including everything you need to know about the spread, over/under, and more. 

Rams vs Panthers Odds: Wild Card Round

All odds in the table below are sourced from BetMGM. Use a BetMGM Bonus Code to juice up your bets. Note that odds may have moved after this article was published. 

Rams vs Panthers Prediction

Sure, the Panthers beat the Rams back in Week 13. But don't let that win trick you into thinking this will be a competitive game. In that loss, Matthew Stafford turned the ball over three times: a tipped, red-zone interception, a strip sack, and a pick-six. It felt like a flukey game at the time. Carolina did nothing to change my mind after that victory. The Panthers dropped three of their following four games, averaging 16.0 PPG during that stretch. Unless Carolina forces three-plus turnovers again, I don't think the Panthers have a chance. 

It feels unfair that Carolina's reward for winning the division is a date with the Rams. Los Angeles was the only team in the league that finished as both a top-10 offense and defense in terms of EPA per play. LA was the league's second-best offense and seventh-best defense in that metric. Carolina, meanwhile, finished outside the top-22 teams in both categories. The Rams should win this one without breaking a sweat. 

• ⭐️ Score Prediction: Los Angeles Rams Win, 28-10

Rams vs Panthers Expert Predictions 

Here's a look at the RotoWire Staff's Rams vs Panthers moneyline predictions: 

• Brandon Justice: Rams
• Tyler Huntington: Rams
• Blake Weishaar: Rams
• Max Staley: Rams

RotoWire Staff Moneyline Prediction Record 

Below, I've detailed the RotoWire staff's moneyline prediction record in the 2025-26 regular season and the NFL Playoffs. 

2025-26 Regular Season: 

• Brandon Justice: 168-104
• Blake Weishaar: 167-105
• Tyler Huntington: 156-116
• Max Staley: 151-121

2025-26 NFL Playoffs: 

• Brandon Justice: 0-0
• Tyler Huntington: 0-0
• Blake Weishaar: 0-0
• Max Staley: 0-0

Where to Bet on NFL Playoffs Odds 

Below, I've listed the major sportsbooks that offer betting markets on this game. I've also included their welcome offers, so you can kickstart your account with some bonus bets.