This article is part of our Yahoo DFS Baseball series.
There are no true aces on Wednesday's night slate, which means you can go after more than one big bat. That points to the Angels-Rangers game, which has an over/under of 11.5 runs, 2.5 more than the next highest game.
PITCHER
Alex Wood, LAD vs. OAK ($47): Wood had food poisoning early in the week, but should be good to go. He went 14 innings in his first two outings with the main issue being zero run support. That'll change in this one, and it helps he gets a beatable Oakland lineup. The A's have been one of the worst against southpaws early this season with a .260 wOBA, 25.4 K% and league-low .065 ISO.
Marco Estrada, TOR at BAL ($39): I don't buy the Blue Jays being underdogs in this game, mainly because of Estrada. He went 13 innings while only giving up four runs in his first two starts against solid Texas and New York squads. The Orioles still haven't figured things out and have ugly numbers across the board against right-handers with a 27.6 K% and .252 wOBA. Estrada should have another quality outing with at least six strikeouts.
CATCHER
Yasmani Grandal, LAD vs. OAK ($12): I don't like any of the catchers in this slate so I'll go against a pitcher who allowed eight runs with only seven Ks in his first two starts. Daniel Mengden continues to struggle for the A's with mediocre numbers against both sides of the plate the last two seasons. He has a .323 wOBA allowed against lefty bats, which meshes well with Grandal's .374 wOBA against righties this season.
FIRST BASE
Albert Pujols, LAA at TEX ($10): Pujols faces Matt Moore, who has given up 12 hits and nine runs in two starts, with most of those coming against right-handed batters. There's a decent chance Moore gets blown up again, and I'm using a couple Angels because of that.
SECOND BASE
Miguel Rojas, MIA vs. NYM ($11): Rojas has provided a solid bat at a cheap price this season, and a lot of his damage has come against righty arms with a .353 wOBA in 37 plate appearances. Zack Wheeler didn't look confident last season and he'll be hard to trust in his first start. In 2017, he struck out righties less (18.0 K%) and allowed an equally bad .348 wOBA against them.
THIRD BASE
Adrian Beltre, TEX vs. LAA ($14): The Angels-Rangers game has the highest over/under by almost three runs, so it wouldn't be a bad idea to stack both lineups. Beltre lacks power at this point in his career, but he's still consistent and has an early .354 wOBA against righties. That should be good enough against Jaime Barria in his major league debut. He's a top prospect, but also young and one that gave up four homers in 9.1 innings of spring ball.
SHORTSTOP
Corey Seager, LAD vs. OAK ($12): This is a perfect spot to go with Seager as he can only hit righty arms and doesn't cost anything. His price is surprisingly down from his average even though he's much better against righties with a .311 wOBA and minimal 12.0 K%. Mengden has been all over the place and struck out just one lefty bat in 20 batters faced.
OUTFIELD
Mike Trout, LAA at TEX ($23): Since the pitchers aren't expensive, I'm going big in the outfield with Trout my first pick. Trout hit only three homers off left-handed pitching last season but already has two this season, and Matt Moore has an early 6.07 xFIP against righties.
Rhys Hoskins, PHI vs. CIN ($22): Hoskins has picked up where he left last season with an early .489 wOBA and .308 ISO against righties. Luis Castillo is all hype and hasn't looked great in his first two starts with 10 ER in 10 IP. If those struggles continue, Hoskins and the Phillies will add to Castillo's 4.34 xFIP against righties this season.
Curtis Granderson, TOR at BAL ($13): After costing less than $10 through the first couple weeks of the season, Granderson finally jumped the threshold. That's partly due to his early .479 wOBA and .240 ISO against righties, but also Kevin Gausman on the mound. The righty has been shaky in his first two starts (9 IP, 12 H, 8 ER) with a lot of that coming against lefty bats as seen in his 6.13 xFIP.