Giants vs. 49ers Betting Odds, Picks and Predictions for Week 9
After a lopsided loss to the Philadelphia Eagles in Week 8, the Giants carry a 2-6 record into Week 9 with the San Francisco 49ers. With injuries mounting, pulling off a win will be a tall order. Let's dig into the betting possibilities for this matchup, highlighting three wagers to consider.
Mike Barner's season record: 25-23 (-2.75 units)
Giants vs. 49ers Betting Odds
Giants: Spread +2.5 (+100 BetMGM), +130 Moneyline (BetMGM)
49ers: Spread -2.5 (-115 DraftKings), -143 Moneyline (BetRivers)
Game Total: Over 47.5 points (-115 ESPNBet), Under 48.5 (-110 Bet365)
Rookie RB Cam Skattebo (ankle) is out for the season, leaving the Giants without yet another one of their best offensive weapons. TE Daniel Bellinger (neck) did not practice Wednesday or Thursday, so he is in danger of being sidelined.
49ers QB Brock Purdy (toe) has been a limited participant in practice, but it's unclear if he will be ready to return for this matchup. QB Mac Jones would start again, if Purdy is not ready. WR Ricky Pearsall (knee) is trending towards missing his fifth straight game.
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Giants vs. 49ers Betting Picks
Christian McCaffrey Over 69.5 rushing yards (-110 DraftKings) for 1 Unit
McCaffrey only has one game this season in which he has rushed for at least 70 yards. That came in Week 7 when he ran for 129 yards and two touchdowns against the Atlanta Falcons. His lackluster yardage total is not because of a lack of opportunities. The 49ers have given him at least 17 carries in all but two of their games. The issue has been him averaging a career-worst 3.5 yards per carry (YPC).
Despite McCaffrey's issues so far, it's the hefty workload that makes the over appealing here. The Giants have been awful against the run, allowing 6.12 YPC to running backs. Last week, the duo of Philadelphia Eagles RBs Saquon Barkley and Tank Bigsby turned 23 rushing attempts into 254 yards. This has the potential to be one of McCaffrey's best stat lines of the season.
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George Kittle Anytime Touchdown Scorer (+135 DraftKings) for 1 Unit
After scoring a touchdown in Week 1 against the Seattle Seahawks, Kittle then missed the next six games because of injury. In his first game back, he failed to catch either of his two targets in a Week 7 matchup with the Falcons. He then got back on track last week, hauling in four of five targets for 43 yards and one touchdown against the Houston Texans.
Last season, Kittle received 21 targets inside the red zone, which helped him record eight touchdowns. The Giants gave up two touchdowns to Eagles TE Dallas Goedert last week, and their secondary could be a problem again with cornerbacks Paulson Adebo (knee) and Cor'Dale Flott (concussion) trending towards being out. At plus-odds, this wager could be well worth the risk.
49ers ML (-145 ESPN Bet) for 1 Unit
The Giants are 0-5 on the road this season, but they are 2-1 at home. That helps their case for at least making this game competitive. The 49ers are 3-2 on the road, and have played well, whether Purdy or Jones has been under center.
The main reason to like the 49ers to win this game is all of the injuries on both sides of the ball for the Giants. Bellinger has been a sneaky productive player for them, so the possibility of him joining Malik Nabers (knee) and Skattebo on the sidelines is not good for the Giants. They are also running out of cornerbacks, and could be starting players that they just plucked off the practice squad or the waiver wire at the position. Let's take the spread out of this and just roll with the 49ers to earn the victory.
Giants vs. 49ers Prediction
We're already on the 49ers to win the game, so let's discuss the total. The 49ers have scored 20 or fewer points in each of their last three games, but they should be aided by the Giants' porous run defense and their injuries at cornerback. Still, the Under might be the way to go because of the Giants being without Skattebo, and the 49ers allowing just 20.5 points per game.
49ers 27, Giants 20












