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Shedeur Sanders
Chance to start remainder of season
Sanders may be Cleveland's starting quarterback for the remainder of the 2025 season, Adam Schefter of ESPN reports.
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Charlie Smyth
Set to make regular-season debut
Smyth is poised to see the first regular-season NFL action of his career Sunday against the Dolphins after being elevated from the Saints' practice squad to the active roster Saturday.
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Jalen McMillan
Gains clearance to practice
McMillan has received clearance from a spine specialist to resume on-field work and is expected to practice ahead of the Buccaneers' game against the Saints in Week 14, Ian Rapoport of NFL Network reports.
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Jayden Daniels
Has chance to play Week 14
Daniels has yet to be cleared for contact but has a "chance" to play in Week 14 against the Vikings, Ian Rapoport of NFL Network reports.
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Tua Tagovailoa
Getting veteran TE back Week 13
The Dolphins' passing game will be bolstered for Sunday's game against the Saints after Tagovailoa's teammate, tight end Darren Waller, was activated from injured reserve Saturday.
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Michael Carter
Could be Cardinals' RB1 for Week 13
Carter would be poised to lead the Cardinals' backfield against the Buccaneers on Sunday if Bam Knight is unable to play due to a knee injury.
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Mo Alie-Cox
Thrust into TE1 role Week 13?
Tyler Warren is listed as questionable for Sunday's game against the Texans due to an illness, and if the rookie is ruled out, then Alie-Cox would be poised to serve as the Colts' No. 1 tight end.
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Patrick Mahomes
Down two more offensive linemen
Mahomes and the Chiefs' offense lost starting offensive tackles Josh Simmons and Jawaan Taylor to injuries during Thursday's 31-28 loss to the Cowboys.
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Will Anderson
Opportunity to build sack count
Anderson and the Texans' pass rush will be facing a Colts' offense Sunday quarterbacked by Daniel Jones -- who is dealing with a fibula injury -- and a Chiefs offense in Week 14 that could be without three of its starting offensive linemen.
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Dillon Gabriel
Might be QB2 for rest of 2025
Gabriel could remain as Cleveland's backup quarterback beyond Week 13, as Adam Schefter of ESPN reports that the Browns are open to starting Shedeur Sanders for the rest of the 2025 season.
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Justin Jefferson
Set to catch passes from rookie QB
J.J. McCarthy was ruled out for Sunday's game against the Seahawks due to being in the league's concussion protocol, which means Jefferson and the rest of the Vikings pass catchers will be hauling in targets from undrafted rookie Max Brosmer.
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Sam Darnold
Facing blitz-happy defense Sunday
Darnold bounced back from a rough outing against the Rams in Week 11 with a two-touchdown performance against the Titans in Week 12, but he faces his old team in the Vikings on Sunday, whose defense leads the NFL with a 44.5 percent blitz rate, Brady Henderson of ESPN reports.
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James Cook
Facing depleted Steelers front
Cook has played a big role in the Bills' league-best rushing attack this season, and he faces a Steelers defense Sunday that will be without rookie defensive lineman Derrick Harmon due to a knee injury, Brooke Pryor of ESPN reports.
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Ashton Jeanty
More carries under new OC?
Ryan McFadden of ESPN believes interim offensive coordinator Greg Olson will deploy more rushing plays for Jeanty for the rest of the regular season, starting with Sunday's AFC West tilt against the Chargers.
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Chris Olave
Uncertain for Week 13
Olave is listed as questionable for Sunday's game against the Dolphins due to a back injury he suffered during Wednesday's practice, Katherine Terrell of ESPN.com reports.
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Kimani Vidal
Retaining top role Sunday
Vidal is slated to serve as the Chargers' No. 1 running back in Sunday's game against the Raiders due to Omarion Hampton remaining on injured reserve, Kris Rhim of ESPN.com reports.
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Omarion Hampton
Remaining out in Week 13
Hampton, who's in the final stages of his recovery from an ankle fracture, has been ruled out for Sunday's Week 13 matchup against the Raiders, Kris Rhim of ESPN.com reports.
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Jameis Winston
Moving to No. 2 role Monday
Winston, who's started the last two games while Jaxson Dart has been in concussion protocol, is slated to serve in the No. 2 QB role during Monday night's game against the Patriots, Jordan Raanan of ESPN.com reports.
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Jaxson Dart
On track to play Monday night
Dart, who's missed the last two games while in concussion protocol, was medically cleared Thursday and is expected to start Monday night against the Patriots, Jordan Raanan of ESPN.com reports.
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Baker Mayfield
Expected to play in Week 13
Mayfield, who exited the Week 12 loss to the Rams with a shoulder injury, is expected to play through his questionable tag in Sunday's Week 13 matchup against the Cardinals, Jenna Laine of ESPN.com reports. "He looked good today, so he is trending to play," head coach Todd Bowles said after practice.
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Mason Rudolph
Reverting to backup role Sunday
Rudolph, who's served as the Steelers' top quarterback for the last six quarters due to Aaron Rodgers' wrist injury, will revert to the No. 2 role for Sunday's game against the Bills, Brooke Pryor of ESPN.com reports.
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Alex Highsmith
Set to return Sunday
Highsmith, who's missed the last two games due to a pectoral injury, has no injury designation for Sunday's game against the Bills, Brooke Pryor of ESPN.com reports.
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DK Metcalf
No injury designation for Week 13
Metcalf, who dealt with an ankle injury during the practice week, doesn't carry an injury designation into Sunday's Week 13 clash against the Bills, Brooke Pryor of ESPN.com reports.
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Aaron Rodgers
Off injury report for Sunday
Rodgers, who missed the Steelers' Week 12 loss to the Bears with a wrist injury, does not carry an injury designation for Sunday's game against the Bills, Brooke Pryor of ESPN.com reports.
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Ross Dwelley
Likely starter Thursday
Dwelley's expected to work as Detroit's top tight end against the Packers on Thanksgiving Day, as Colton Pouncy of The Athletic reports that Brock Wright has been ruled out due to a neck injury.
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